Electron Microscopic Studies on Human Basophils from Atopic and Nonatopic Subjects, Using Horse Radish Peroxidase Labelled Anti-IgE

Elven, E.H. van; Stallman, P.J.; Brühl, P

doi:10.1159/000231877

Cited by 5 publications

(1 citation statement)

References 15 publications

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“…; Komiyama and Spicer, 1974;van Elven et al, 1977). Ackerman (1963a) presents an excellent review and comparison of basophil cytochemistry in several mammalian species, including man; he also compares and contrasts the basophil with the mast cell.…”

Section: Considerable Information Regarding the Morphology And Cytochmentioning

confidence: 99%

Cytochemistry of the Blood Basophil of Bufo marinus

Cannon¹,

Sampson²,

Kapes³

et al. 1988

Journal of Herpetology

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JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact support@jstor.org.. Society for the Study of Amphibians and Reptiles is collaborating with JSTOR to digitize, preserve and extend access to Journal of Herpetology.ABSTRACT. -The morphology and cytochemistry of the blood basophil of Bufo marinus are characterized, and compared and contrasted to the basophil from several other amphibians and with the mammalian basophil. The basophil of B. marinus contains at least one type of mucopolysaccharide and an acid mucopolysaccharide, possibly heparin, within the cytoplasmic granules. Several amino acids, but no histidine, and no lipid, occur in B. marinus basophils. Furthermore, these basophils appear devoid of hydrolytic enzymes, excepting nonspecific esterase. They do possess numerous oxidative enzymes, however, in the intergranular cytoplasm. The basophil of B. marinus is more similar cytochemically to the mammalian basophil than to the basophil of several previously studied amphibians.

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Section: Considerable Information Regarding the Morphology And Cytochmentioning

confidence: 99%

Cytochemistry of the Blood Basophil of Bufo marinus

Cannon¹,

Sampson²,

Kapes³

et al. 1988

Journal of Herpetology

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Basophils and Mast Cells: Structure, Function, and Role in Hypersensitivity

Galli

Dvorak

1979

Cellular, Molecular, and Clinical Aspects of Allergic Disorders

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httroductionSeveral important discoveries of the past few decades have launched a renaissance of research into basophil and mast cell function. These include the discovery of IgE and its affinity for basophils and mast cells and the demonstration of the ability of these cells to elaborate and release not only histamine but also a variety of lowmolecular-weight mediators of immediate hypersensitivity. Moreover, the application of modern methods of tissue fixation and processing has permitted confident identification of basophils and mast cells with both the light and electron microscopes in diverse experimental and clinical situations, and has clearly implicated these cells in a variety of delayed-onset immunological phenomena where their participation had been entirely unexpected. This chapter will selectively review current knowledge regarding basophil and mast cell structure, function, and roles in hypersensitivity phenomena. We will particularly emphasize findings that implicate basophils and mast cells in immunological reactions of delayed onset, because we feel that the study of such phenomena is likely to elucidate the normal immunological functions of these cells. Whenever possible, the data presented will be derived from human studies. However, in many instances, information about human mast cells and basophils is sparse or lacking altogether. For this reason, significant conclusions derived from animal experiments are included when appropriate.

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Histamine Content and Secretion in Basophils and Mast Cells

Dvorak

1998

Progress in Histochemistry and Cytochemistry

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Electron Microscopic Studies on Human Basophils from Atopic and Nonatopic Subjects, Using Horse Radish Peroxidase Labelled Anti-IgE

Cited by 5 publications

References 15 publications

Cytochemistry of the Blood Basophil of Bufo marinus

Cytochemistry of the Blood Basophil of Bufo marinus

Basophils and Mast Cells: Structure, Function, and Role in Hypersensitivity

Histamine Content and Secretion in Basophils and Mast Cells

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