Electron Microscopic Study of the Intracellular Activity of Alkaline Phosphatase in the Hypertrophic Chondrocytes of Epiphyseal Cartilage

Takagi, Minoru; Takagi, Hideo D.; Kojima, Noboru; Kasuya, Kenji; Toda, Yoshihisa

doi:10.2334/josnusd1959.19.103

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1981

2012

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“…Ultrastructurally, plenty of matrix vesicles (MVs; Anderson, 1967Anderson, , 1969Bonucci, 1967Bonucci, , 1970 are found in these zones. These are the TNAP-rich MVs first described by Matsuzawa and Anderson (1971) and later confirmed for both types of cartilage (Akisaka & Gay, 1985;Takagi & Toda, 1979;Takechi & Itakura, 1995a, 1995b. When these TNAP-rich MVs are isolated and cultured in mineralizing solutions, they show mainly extravesicular apatite deposition (Boskey et al, 1994).…”

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confidence: 75%

Advanced Topics in Biomineralization

Seto¹

2012

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ley and completed his Ph.D. in bone architecture and mechanics at the Max-Planck-Institute of Colloids and Interfaces in 2010. His current research interests include development of in situ measurements of organic-inorganic interactions in calcium carbonate and phosphate mineralization systems as well as structure-function relationships in biological materials. He is currently a research fellow working with Prof. Helmut Cölfen at the Universität Konstanz and enjoys cycling, hiking, as well as skiing outdoors in the nearby Alps.

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