Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts

Bowler, Russell P.; Hansel, Nadia N.; Jacobson, Sean; Barr, R. Graham; Make, Barry J.; Han, MeiLan K.; O’Neal, Wanda K.; Oelsner, Elizabeth C.; Casaburi, Richard; Barjaktarević, Igor; Cooper, C.B.; Foreman, Marilyn G.; Wise, Robert A.; DeMeo, Dawn L.; Silverman, Edwin K.; Bailey, William C.; Harrington, Kathy; Woodruff, Prescott G.; Drummond, M. Bradley

doi:10.1007/s11606-017-4150-7

Cited by 83 publications

(75 citation statements)

References 28 publications

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“…33 Other studies of adults with COPD show that e-cigarette use is associated with a heavier conventional cigarette smoking history and poorer health outcomes. 34 It is possible that pulmonary toxicity associated with e-cigarette use exists across all the categories of cigarette smoking status, including among those who had never smoked tobacco cigarettes. 27,33,34 As the prevalence of e-cigarette use continues to rise, 33 more longitudinal research is needed to confirm the causal relationship between regular e-cigarette use and poor physical health among workers diagnosed with COPD.…”

Section: Substance Use and Abuse Behaviorsmentioning

confidence: 99%

Health Risk Disparities among Employed Adults with COPD Living in Central Appalachian U.S. States

Stellefson

Wang

Balanay

et al. 2020

American Journal of Health Education

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Background: Little is known about risk factors associated with poor health among employees with COPD living in Central Appalachia. Purpose: Determine variability in health distress based on risk factors, including race and income, among employees with COPD from Central Appalachian U.S. States. Methods: 2016-2017 BRFSS data were analyzed from employed adults with COPD living in KY, NC, TN, and WV (N = 1,326). Health risks included (1) comorbidities; (2) substance use/abuse; and (3) limited healthcare access as predictors of mental and physical distress, with race and income entered as covariates. Results: Respondents reporting several comorbidities were more likely to report physical and mental distress compared to those without comorbidities. Workers who used e-cigarettes on some versus no days were more likely to report physical distress. Those reporting cost preventing access to medical care versus no cost barriers were more likely to report physical and mental distress. Low-income workers were more likely than higher-income workers to report distress. Discussion: Comorbidities, e-cigarettes, and high medical costs are potential causes of occupation-related disability among employees with COPD working in Central Appalachian U.S. States. Translation to Health Education Practice: Worksite interventions should address risks negatively associated with health outcomes among workers with COPD from Central Appalachia.

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Section: Substance Use and Abuse Behaviorsmentioning

confidence: 99%

Health Risk Disparities among Employed Adults with COPD Living in Central Appalachian U.S. States

Stellefson

Wang

Balanay

et al. 2020

American Journal of Health Education

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“…The longterm impact of the consumption of such products is still being investigated. A study of 3536 Genetic Epidemiology of COPD (COPD-Gene) and 1060 SPIROMICS current or former cigarette smokers found that 12-16% of participants ever used e-cigarettes and that 5% were current users 9 . Although close to 90% of ever-users reported using e-cigarettes in order to help decrease or quit consumption of regular cigarettes, these goals were not consistently reached at the 5-year follow-up visit.…”

Section: Exposuresmentioning

confidence: 99%

Insights into Chronic Obstructive Pulmonary Disease Epidemiology, Phenotypes and Outcomes from SPIROMICS

Labaki¹,

Martínez²,

Han³

2021

BRN

Self Cite

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SubPopulations and InteRmediate Outcome Measures in COPD Study (SPIROMICS) is a multicentre National Institutes of Health funded cohort study of nearly 3000 never-smokers and ever-smokers (≥ 20 pack-years) with and without chronic obstructive pulmonary disease (COPD). It was designed to help fill gaps in our understanding of the biological complexity and clinical heterogeneity of COPD. The original goals for this study were to identify subgroups of smokers who may benefit from targeted therapies and to discover and validate intermediate biomarker endpoints. Here we review important findings from SPIROMICS over the past five years, including the impact of environmental and occupational exposures on the respiratory health of smokers, the characterisation of symptomatic smokers with preserved pulmonary function and the investigation of several diagnostic and prognostic biomarkers such as airway mucin concentration, functional small airways disease on chest computed tomography and a gene expression signature of interleukin 17A response in airway epithelium.

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“…However, the new forms of smoking, with heat-not-burn tobacco, and vaping, will surely impact prevalent and new cases of COPD [16,17]. There is only one prescription needed to measure the burden of all these forms of COPD patients [18], and successfully overcoming their many challenges: monitoring trends by shoe-leather epidemiology [19], complemented by Big Data and other new technologies [20], such as AI.…”

mentioning

confidence: 99%

The evolution of COPD species; or, something is changing for good in COPD

Soriano

2019

Eur Respir J

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Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts

Cited by 83 publications

References 28 publications

Health Risk Disparities among Employed Adults with COPD Living in Central Appalachian U.S. States

Health Risk Disparities among Employed Adults with COPD Living in Central Appalachian U.S. States

Insights into Chronic Obstructive Pulmonary Disease Epidemiology, Phenotypes and Outcomes from SPIROMICS

The evolution of COPD species; or, something is changing for good in COPD

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