“…[9][10][11][12][13] In addition, it has also been reported that significant changes are not detected in the amplitude or implicit time of the mfERG after altering the contrast of the pattern stimuli in eyes with POAG. 14 On the other hand, some studies of glaucomatous eyes of experimental animals and humans 2,[5][6][7][15][16][17][18][19] have shown that the waveforms of the first-order kernel of the mfERG reflect the functioning of the cells in the inner layers of the retina, particularly cells in the ganglion cell layer. When the sodium-based action potentials of ganglion cells and amacrine cells were blocked by intravitreal tetrodotoxin in monkey eyes, the amplitude of a small positive wave, which appeared after P1 of the first-order component of the mfERG, was attenuated or disappeared.…”