Electrophysiological features in dogs with peripheral nerve sheath tumors: 51 cases (1993–2010)

Chevoir, Matthias Le; Thibaud, Jean Laurent; Labruyère, Julien; Uriarte, Ane; Fornel-Thibaud, P De; Moissonnier, P.; Delisle, F.; Blot, Stéphane

doi:10.2460/javma.241.9.1194

Cited by 20 publications

(19 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to previous surveys, male predominance (71.4% and 58.8%) was reported in two studies [2,12] and female predominance was described in one study [5]. Interestingly, three female cases around mammary glands in this study were confirmed as malignant PNST.…”

Section: Discussionsupporting

confidence: 59%

“…Of the 51 PNSTs reported previously in dogs, the limb affected was thoracic in 40 dogs and pelvic in 11 dogs [12]. In contrast, the prevalence of PNSTs in hindlimb was two times higher than those in forelimb in this study.…”

Section: Discussioncontrasting

confidence: 55%

“…The limb affected in this study was left in 5 dogs and right in 4 dogs. The clinical signs in dogs with PNSTs were chronic progressive lameness in affected limb, muscular atrophy, hyporeflexia, palpable mass, and pain on palpation [2,12]. Severe muscular deformity in hindlimb and neurologic signs were observed in two dogs with malignant PNST in present study.…”

Section: Discussionmentioning

confidence: 61%

See 2 more Smart Citations

Cutaneous peripheral nerve sheath tumors in 15 dogs

Ko¹,

Song²,

Kang³

et al. 2014

Korean Journal of Veterinary Research

View full text Add to dashboard Cite

: Peripheral nerve sheath tumors (PNSTs) are heterogeneous tumor groups of peripheral nerves that originate from either Schwann cells or modified Schwann cells, fibroblasts, or perineural cells. In this study, signalment and clinical data such as tumor location and size were evaluated for 15 cases of PNSTs collected from local animal hospitals. The mean age of dogs with malignant PNST was higher than that of dogs with benign PNST. Additionally, the male to female ratio in dogs with PNST was 1 : 4. In dogs with PNST, the primary sites of involvement were the hindlimb, forelimb, around the mammary glands, the neck, and the abdomen. Histiopathologic examination revealed that eight PNSTs were benign and seven were malignant. The tumor cells were composed of loosely to densely arranged interlacing bundles and wavy spindle cells arranged in short bundles, palisading, and whirling. High mitotic figures, local invasion, multifocal necrosis and atypical multinucleated giant cells were observed in malignant PNST cases. All PNSTs showed immunoreactivity for vimentin and S-100. However, only 93.3% and 73.3% were immunoreactive for NSE and GFAP, respectively. Overall, these results indicated that immunohistochemical markers such as vimentin, S-100 and NSE could help confirm the diagnosis of canine PNSTs.

show abstract

Section: Discussionsupporting

confidence: 59%

Section: Discussioncontrasting

confidence: 55%

Section: Discussionmentioning

confidence: 61%

See 1 more Smart Citation

Cutaneous peripheral nerve sheath tumors in 15 dogs

Ko¹,

Song²,

Kang³

et al. 2014

Korean Journal of Veterinary Research

View full text Add to dashboard Cite

show abstract

“…Motor nerve conduction velocity (MNCV) testing is valuable in the detection of neuromuscular diseases: inherited and acquired polyneuropathies (Shelton et al 2003;Gabriel et al 2006;Vanhaesebrouck et al 2008), general weakness (Jeffery et al 2006), botulism (Uriarte et al 2010), neuromuscular junction disorders (Meriggioli and Sanders 2005), polyradiculoneuritis (Hirschvogel et al 2012), cauda equina syndrome (Sekiguchi et al 2008), or peripheral nerves tumours (Le Chevoir 2012). Conduction velocity is defined as the speed at which an action potential propagates along a nerve.…”

mentioning

confidence: 99%

Electroneurography of the ulnar nerve in dogs

et al. 2014

View full text Add to dashboard Cite

Electroneurography as one of the electrodiagnostic techniques is used to measure the speed of action potential which is propagated down the nerve after stimulation. It gives information about normal functioning of the peripheral nerves. The aim of this study was to evaluate the applicability of a new electroneurographic technique by performing motor nerve conduction velocity measurements in the ulnar nerve with surface stimulating electrodes in healthy dogs, to correlate the obtained data by age, limb length, rectal temperature, and sex; and to compare these results with published findings utilizing needle stimulating electrodes. The study was performed in 24 clinically healthy dogs without anaesthesia. Rectal temperatures and limb lengths were measured in all individuals. There were significant correlations among several indicators (age, rectal temperature, limb length, conduction velocity, latency and duration of compound muscle action potentials). Limb length was found to have a significant effect on the duration of the compound muscle action potential from both stimulation sites (proximal/distal; r = 0.71, r = 0.68, P < 0.01), but there was no effect on the conduction velocity or amplitude of the action potentials. There was no significant difference (P > 0.05) in the measured indicators between males and females, even though females had a higher mean conduction velocity than males. These results prove that conduction velocity measurements in dogs could be performed non-invasively, without a danger of infection or haematomas or complications with anaesthesia, which is more favourable and time-saving for clinical practice, and more comfortable for patients.

show abstract

“…EMG recordings were taken in the corresponding muscles of the left (unaffected) forelimbs. Spontaneous electrical activity following denervation was quantified using a subjective scale: 0 = electrically silent muscle; + = rare spontaneous activity recorded at few sites; ++ = diffuse occasional spontaneous activity or frequent spontaneous activity recorded at few sites; and +++ = diffuse abundant spontaneous activity in the muscle. The level of spontaneous activity was variable.…”

Section: Clinical Reportmentioning

confidence: 99%