Electrophysiological Testing

Issa, Ziad F.; Miller, John M.; Zipes, Douglas P.

doi:10.1016/b978-0-323-52356-1.00004-9

Cited by 9 publications

(7 citation statements)

References 63 publications

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“…Printing speed 0.1 mm/s -5 cm/s 1-10,000 droplets 1,600 mm/s (Xu et al, 2009), (Hopp et al, 2012), (Guillotin et al, 2010), (Kim et al, 2010), (Cui et al, 2012a) with a certain spatial pattern that has high resolution stimulation of the heart (Mir & Nakamura, 2017). High resolution stimulation of is a method of evaluation of the functional attributes of the cardiac tissue and means of induction of various arrhythmia (Issa et al, 2019). Briefly, the 3D bioprinting procedure begins with the gathering of the patient's data through imaging tools like computed tomography (CT), magnetic resonance imaging (MRI) to design a computer-aided design (CAD) model.…”

Section: Referencesmentioning

confidence: 99%

3D Bioprinting Technology – One Step Closer Towards Cardiac Tissue Regeneration

Chingale

Cheng

2022

Front. Mater.

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Cardiovascular diseases are one of the leading causes of death across the globe. Heart transplantation has been used for end stage heart failure patients. However, due to the lack of donors, this treatment option usually depends on multiple variables and the result varies due to immunological issues. 3D bioprinting is an emerging approach for in vitro generation of functional cardiac tissues for drug screening and cardiac regenerative therapy. There are different techniques such as extrusion, inkjet, or laser-based 3D printing that integrate multiple cell lines with different scaffolds for the construction of complex 3D structures. In this review, we discussed the recent progress and challenges in 3D bioprinting strategies for cardiac tissue engineering, including cardiac patches, in vitro cardiac models, valves, and blood vessels.

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Section: Referencesmentioning

confidence: 99%

3D Bioprinting Technology – One Step Closer Towards Cardiac Tissue Regeneration

Chingale

Cheng

2022

Front. Mater.

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“…Muscle force is the sum of forces of all activated MUs. The processes behind the activation of a MU can be summarized as follows [7]:…”

Section: Introductionmentioning

confidence: 99%

An integrated mathematical model of the neuromuscular activity of a motor unit

Ivanova,

Ivanov,

Raikova

2023

Preprint

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In the present work, we propose a new integrated mathematical model for the neuromuscular activation of a motor unit, describing the four consecutive processes, leading to muscle contraction—neural impulse propagation, acetylcholine transport in the neuromuscular junction, calcium release in the muscle cell, and force generation. We connect in an appropriate way models of the respective processes, known from the literature, and validate the resulting model by showing that it can reproduce with high accuracy experimental data for two motor unit twitches on a rat medial gastrocnemius muscle and can numerically restore the sequence of events that result in force generation. Sensitivity analysis for some of the model parameters is further performed to study their effect on the model solutions and to show that they can be related to known malfunctions or treatments of the neuromuscular system.

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“…Histologicamente, possuem 5-10mm de comprimento e 0,1-7mm de espessura, percorrem o sulco atrioventricular em profundidade variável (endo a epicárdio) e podem apresentar curso longo, oblíquo ou mesmo se ramificar em diversos pontos (2) . Podem ainda estar relacionadas com outros defeitos cardíacos congênitos, como a anomalia de Ebstein, ou mutações genéticas específicas, como a PRKAG2 (3) (4) .…”

Section: Conceitos Gerais Em Vias Acessóriasunclassified

“…O espectro de manifestações clínicas decorrentes da presença de uma VA está relacionado às características eletrofisiológicas da mesma e do sistema de condução nativo do indivíduo. Em pacientes cuja VA possua condução anterógrada, o fenômeno eletrocardiográfico de pré-excitação ventricular manifesta pode ser identificado pelo encurtamento do intervalo PR (<120ms) e ativação mais lenta (onda delta) do início do QRS, que apresenta duração aumentada (>120ms) (2)(3) (4) . Tais achados decorrem da despolarização prematura dos ventrículos antes que o impulso elétrico sinusal atravesse o nó atrioventricular (NAV) e alcance as terminações distais do sistema His-Purkinje.…”

Section: Conceitos Gerais Em Vias Acessóriasunclassified

“…Aproximadamente 90% da energia aplicada é imediatamente absorvida em um raio de 1 a 1,5mm ao redor da ponta do cateter, denominado aquecimento resistivo (2) (4) . Por outro lado, os 10% restantes são lentamente dispersados para regiões adjacentes através da dissipação do calor, chamado de aquecimento condutivo (2) (4) .…”

Section: Ablação Por Radiofrequência De Vias Acessórias Para-hissianasunclassified

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Eficácia e segurança da ablação por cateter de vias acessórias para-hissianas: estudo randomizado comparativo entre crioablação e radiofrequência

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Electrophysiological Testing

Cited by 9 publications

References 63 publications

3D Bioprinting Technology – One Step Closer Towards Cardiac Tissue Regeneration

3D Bioprinting Technology – One Step Closer Towards Cardiac Tissue Regeneration

An integrated mathematical model of the neuromuscular activity of a motor unit

Eficácia e segurança da ablação por cateter de vias acessórias para-hissianas: estudo randomizado comparativo entre crioablação e radiofrequência

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