Electrophysiology in Disorders of Consciousness: From Conventional EEG Visual Analysis to Brain-Computer Interfaces

EEG functional connectivity contributes to outcome prediction of postanoxic coma

“…The post-hoc analysis revealed an increased functional connectivity in the delta and beta2 bands, which is in accordance with literature. Previous studies report an association between poor outcome and increased power or connectivity in these bands, both in postanoxic comatose patients and subjects showing minimally conscious or vegetative state (Nenadovic et al 2014;S ßerban et al 2017;Chatelle et al 2018). On the other hand, connectivity in the theta and alpha bands had a different behaviour.…”

“…Finally, we study the additional predictive value of functional connectivity features to state-of-the-art prognostication using quantitative non-coupling EEG features. Previous electrophysiology studies focused in postanoxic coma patients or subjects with consciousness disorders have found that a decreased connectivity or power in the alpha band and an increase in these parameters in the delta band is associated with poor outcome (Nenadovic et al 2014;Hong and Su 2017;S ßerban et al 2017;Chatelle et al 2018). Therefore, we hypothesize that similar changes in connectivity in these bands will be observed, and that the parameters obtained from these frequency bands will have a higher relevance in the prediction of outcome of postanoxic coma patients.…”