Electrophysiology in the Guillain-Barré Syndrome: Study of 30 Cases

Kundu, NC

doi:10.3329/jbcps.v24i2.149

Cited by 3 publications

(6 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is almost consistent with the study of Kundu 23 where he observed AIDP 33.3%, AMSAN 26.66%, AMAN and AIDP 26.66% and AMAN 13.33%. But another study in Bangladesh showed that electrophysiologically 67% patients had axonal variant of GBS.…”

Section: Discussionsupporting

confidence: 80%

“…White blood cell count was below 5/mm 3 in all patients. Similar findings were found by Kundu 23 who observed in his study that cerebrospinal fluid protein was elevated in 90.0% patients and in 93.3% cases cerebrospinal fluid total cell count was up to 5 cells/mm 3 and in only 6.7% patients total cell count was up to 15 cells/mm 3 .…”

Section: Discussionsupporting

confidence: 76%

“…Alam et al 21 had shown in their series the age of patients from 4-83 years. Similarly, Arami et al 22 and Kundu 23 had observed age from 6-79 years and 12-67 years respectively.…”

Section: Discussionmentioning

confidence: 99%

“…22,24,26,27 But the studies done in Asian subcontinent 20,23,28 gastroenteritis was the most frequent previous event. Kundu 23 had found fever alone or in combination with loose motion as the commonest antecedent event (36.66%) followed by loose motion (23.33%). Kalita et al 28 found diarrhea in 37.15% and upper respiratory tract infection in 17.14% of the patients.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Study of Cerebrospinal Fluid (CSF) and Clinical and Electrophysiological Features of Hospitalized Patients with Gullain-Barre´ Syndrome

Huda¹,

Khan²,

Azam

et al. 2015

J Enam Med Col

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 80%

Section: Discussionsupporting

confidence: 76%

“…Alam et al 21 had shown in their series the age of patients from 4-83 years. Similarly, Arami et al 22 and Kundu 23 had observed age from 6-79 years and 12-67 years respectively.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Study of Cerebrospinal Fluid (CSF) and Clinical and Electrophysiological Features of Hospitalized Patients with Gullain-Barre´ Syndrome

Huda¹,

Khan²,

Azam

et al. 2015

J Enam Med Col

View full text Add to dashboard Cite

show abstract

“…In addition, mean age of patients is lower in AMAN (2nd decades) and AMSAN (3rd decades) than AIDP in this study. [11][12][13][14] About twothirds patients (62.86%) presented with both upper and lower limbs weakness whereas one-third (31.43%) complained of facial weakness and 13.2% has bulbar paralysis. Antecedent events are present in two thirds of the patients (66%) in preceding weeks (one to four weeks).…”

Section: Discussionmentioning

confidence: 99%

Electrophysiological patterns in patient with Guillain-Barre syndrome

Hossain¹,

Ali

Rahman

et al. 2021

Birdem Med J

View full text Add to dashboard Cite

Background: Guillain-Barre syndrome (GBS) is an acute, frequently severe and fulminant polyradiculoneuropathy that is autoimmune in nature. Incidence and predominant subtypes of GBS differ geographically. Electrophysiology has important role in subtyping GBS. This study aimed to evaluate the electrophysiological findings in patient of GBS. Methods: This was a hospital based cross-sectional descriptive study and conducted at the Department of Neurology in Sir Salimullah Medical College & Mitford Hospital, Dhaka and National Institute of Neurosciences and Hospital, Dhaka during July 2017 to June 2018. Clinically diagnosed 53 patients with GBS were enrolled according to prefixed selection criteria. Detail history taking, clinical examination, nerve conduction study and cerebrospinal fluid (CSF) examination was performed in all cases. Clinical findings, nerve conduction study (NCS) parameters, CSF findings and demographic profiles were evaluated. Results: Mean ± SD age of presentation was 41.64 (±14.56) years and median age was 42.0 years. There were total 33(62 %) males and 20 (38 %) females with male: female ratio of 1.7:1. Clinically two-thirds(62.3%) of patients had both upper and lower limb involvement (62.3%), facial weakness was in 32.1% and 13.2% had bulbar involvement. Acute inflammatory demyelinating polyneuropathy (AIDP), acute motor axonal neuropathy (AMAN) and acute motor sensory axonal neuropathy (AMSAN)were found to be 51%, 32% and 17% respectively. CSFprotein was elevated in most of the patients with a range of 16-725 mg/dl. Highest CSF protein was found in AIDP. Conclusion: Electrophysiological studies play an important role in the early detection; characterization of GBS.In this study, the commonest type of GBS was AIDP. Higher levels of CSF protein, absent H-reflex and Fresponse, sural sparing and unexcitable nerves are more frequently present in AIDP. BIRDEM Med J 2022; 12(1): 16-21

show abstract

Clinical, Autonomic & Electrophysiological Features in Patients with Guillain Barre Syndrome in a Tertiary Care Hospital of Bangladesh

Jannat

Hannan

Alam

et al. 2019

Bangla. J. Neuroscience

View full text Add to dashboard Cite

Background: Guillain-Barre Syndrome (GBS) is the most common cause of acute flaccid paralysis in the adult population. It is an acute post infectious immune mediated peripheral neuropathy with a marked variation in pathology, clinical presentation and prognosis. Objective: The aim of the study were to evaluate clinical profile, to assess autonomic involvement & electrophysiological findings in adult patients with GBS. Methods: An observational, cross sectional study was carried out in the Department of Neurology, BSMMU, Dhaka from March, 2015 to September, 2017. Total 43 patients of GBS fulfilling the inclusion criteria were recruited as the study population. Detailed clinical examination, CSF study & nerve conduction study were done. Disability status was measured by Hughes functional grading scale. For autonomic assessment 35 adult healthy control were also included for comparison. Then following tests of autonomic nervous system were performed in both patient and control group 1) resting heart rate and heart rate on changing posture (30: 15 ratio) 2) supine blood pressure and blood pressure on changing posture 3) heart rate response to valsalva maneuver 4) heart rate response to deep breathing and E: I ratio 5) sphincter disturbance by symptoms questionnaire. Results: The mean age of patients was 35±12 years (range18 to 65 years) with slight male predominance (58.1%). Major clinical presentation was weakness of all 4 limbs followed by sensory complaints (44.2%). 7% of the patient had breathing difficulty and dysphagia. Only 4.7 % had diplopia. Among the symptoms of autonomic dysfunction most common symptoms was constipation (30.2 %) followed by palpitation (14%), urinary retention (7%), lightheadedness and urinary incontinence (4.7%). Cranial nerve palsy was present in 34.9% of cases among them facial palsy was found commonly (27.9%), followed by bulbar palsy (7%) and ophthalmoplegia (4.7%). One patient (2.3%) had both facial palsy and ophthalmoplegia. AIDP, AMAN and AMSAN subtypes comprised 32.6%, 37.2% and 20.9% of cases respectively. Regarding autonomic dysfunction variation of heart rate by different maneuver like posture change, deep breathing and valsalva maneuver was found commonly. 30:15 ratio was abnormal in majority of the patients (82.4%) followed by abnormal max-min HR/min on deep breathing (58.1%) and abnormal valsalva ratio (37.2%). Other abnormalities were postural hypotension (38.2%), sinus tachycardia (25.6%), hypertension (16.3%), hypotension (4.7%), and sinus arrhythmia (4.7%). Bowel bladder dysfunction was another autonomic dysfunction among them constipation 30%, urinary retention 7% and urinary incontinence 4.7% of cases. Conclusion: GBS can be presented with variable presentation including autonomic dysfunction. In this study common clinical presentation was limb weakness & different patterns of autonomic dysfunction was found in patients with GBS. Common electrophysiological subtype was AMAN. So in addition to clinical & electrophysiological analysis autonomic evaluation is essential in every patients with GBS as autonomic dysfunction is one of important cause of mortality. Bangladesh Journal of Neuroscience 2019; Vol. 35 (2): 57-62

show abstract

Electrophysiology in the Guillain-Barré Syndrome: Study of 30 Cases

Cited by 3 publications

References 25 publications

Study of Cerebrospinal Fluid (CSF) and Clinical and Electrophysiological Features of Hospitalized Patients with Gullain-Barre´ Syndrome

Study of Cerebrospinal Fluid (CSF) and Clinical and Electrophysiological Features of Hospitalized Patients with Gullain-Barre´ Syndrome

Electrophysiological patterns in patient with Guillain-Barre syndrome

Clinical, Autonomic & Electrophysiological Features in Patients with Guillain Barre Syndrome in a Tertiary Care Hospital of Bangladesh

Contact Info

Product

Resources

About