With the introduction of electroanatomic mapping systems, electrical voltage maps of the chamber of interest and activation maps of arrhythmias have emerged as invaluable tools for successful ablation of focal and reentrant arrhythmias.(1) In reentrant rhythms that cause hemodynamic instability, substrate modification has been demonstrated to achieve meaningful results.(2,3) In arrhythmias where a scar serves as the substrate for reentry, activation maps and voltage maps must be acquired and displayed separately. During isochronal activation mapping, a fiduciary activation point is chosen and all mapped points are represented in relation to this reference. The inherent limitation in such mapping is in the assignment bias, where the subjective selection of an individual local potential within a multi-component electrogram can drastically alter a propagation map. Depending on whether the first component or last component of a split or multi-component potential is chosen, "early" activation can be made "late" and vice versa.
The Present StudyIn this issue of the Journal, Linton and colleagues present a novel form of electroanatomic mapping called "ripple mapping", whereby voltage, timing, and location are simultaneously displayed with continuous display of electrograms that were previously sampled and 'postprocessed'. (4) The goals of this proof-of-concept study were to (i) simplify activation mapping by minimizing operator-dependence, (ii) eliminate interpolation of data between mapped points and (iii) to eliminate assignment bias by developing software to register continuous or fractionated electrograms, thereby removing a single, isolated local value as a representative of an entire coordinate. A large window was sampled, 500 ms before and after the QRS, and electrograms were time-gated and displayed as dynamic bars protruding from the surface changing in length and color depending on the local electrogram voltage-time relationship. With an analysis of sinus rhythm activation, three atrial tachycardias, and two ventricular tachycardias, the authors display ripple maps for arrhythmias due to reentrant mechanisms with successful ablation at sites of continuous activity in four of five patients.The outlined objectives were met and the videos demonstrate a more user friendly display of activation. However, several limitations must be noted. Although demonstrated in common arrhythmias, the application of this software to clinical practice is likely to be necessary only Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. 5,6). However, far field potentials will pose a challenge fo...