Electropolymerization of Thin Film Conducting Polymer and Its Application for Simultaneous Determination of Ascorbic Acid, Dopamine and Uric Acid

Abstract

In this paper electropolymerization of a thin film of para-phenylenediamine (PPD) is studied at glassy carbon electrode (GCE) in sulfuric acid media by cyclic voltammetry. The results showed that this polymer was conducting and had a reproducible redox couple in the potential region from 0.0 to 0.4 V in phosphate buffer solution. This modified GCE (p-PPD-GCE) was applied for simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA) using differential pulse voltammetry (DPV). The p-PPD-GCE in 0.1 M phosphate buffer solution (pH 5.0) separated the DPV signals of AA, DA and UA with sufficient potential differences between AA-DA and DA-UA and also enhanced their oxidation peak currents. The oxidation currents were increased from 2.0 to 2000.0 mM for AA, 10.0 to 1250.0 mM for DA and 50.0 to 1600.0 mM for UA. The detection limits were evaluated as 0.4, 1.0 and 2.5 mM for AA, DA and UA, respectively (S/N = 3).

Simultaneous determination of captopril, acetaminophen and tryptophan at a modified electrode based on carbon nanotubes

“…They have found a vast range of important applications in the fields of clinical, industrial, environmental, and agricultural analyses [5][6][7]. The modification of electrodes using redox modifiers is an interesting field in analytical chemistry.…”

Electrochemical determination of ascorbic acid, uric acid and folic acid using carbon paste electrode modified with novel synthesized ferrocene derivative and core–shell magnetic nanoparticles in aqueous media

“…There are several techniques for measuring AA levels, including high-performance liquid chromatography, [2] spectrophotometry, [3] liquid chromatography, [4] capillary electrophoresis, [5] chemiluminescence [6] and electrochemical methods. [13] FA as one of the water-soluble vitamins contributes to the construction of healthy cells, as FA deficiency is one of the leading causes of anaemia. The UA level is currently measured using colorimetric, enzymatic and electrochemical techniques.…”

Enhanced electro-oxidation of urea based on nickel nanoparticle decorated reduced graphene oxide/PEDOT:PSS composite

“…Another important category of novel materials for various electrochemical applications is Conductive Polymers (CPs). CPs have emerged as intelligent materials that can be applied for the development of various devices such as sensors due to their radically distinctive properties, such as high conductivity, light weight, and excellent processability [22,23]. In recent years, interest in the preparation of nanocomposites of conducting polymers and graphene has been put on notice intensively due to cooperating for enhanced e ects resulting from the combination of these two classes of compounds [24][25][26].…”