We present a model for electron-and neutrino-scattering off nucleons and nuclei focussing on the quasielastic and resonance region. The lepton-nucleon reaction is described within a relativistic formalism that includes, besides quasielastic scattering, the excitation of 13 N * and ∆ resonances and a non-resonant single-pion background. Recent electron-scattering data is used for the state-ofthe-art parametrizations of the vector form factors; the axial couplings are determined via PCAC and, in the case of the ∆ resonance, the axial form factor is refitted using neutrino-scattering data. Scattering off nuclei is treated within the Giessen Boltzmann-Uehling-Uhlenbeck (GiBUU) framework that takes into account various nuclear effects: the local density approximation for the nuclear ground state; mean-field potentials and in-medium spectral functions. Results for inclusive scattering off Oxygen are presented and, in the case of electron-induced reactions, compared to experimental data and other models.