Electrospinning cellulose acetate/silk fibroin/Au-Ag hybrid composite nanofiber for enhanced biocidal activity against MCF-7 breast cancer cell

Arumugam, Mayakrishnan; Murugesan, Balaji; Nithya, P.; Chinnalagu, Dhilip kumar; Rangasamy, Gowri; Muthusubramanian, Shanmugam

doi:10.1016/j.msec.2021.112019

Cited by 56 publications

(22 citation statements)

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“…In the development, regeneration and characterization of a blended system combining Bombyx Mori silk fibroin protein and cellulose acetate, a cellulose derivative, silk may be mixed with cellulose derivatives [119]. Many studies on the combination of silk and cellulose acetate for filament/fibre manufacturing may be found in the literature [106,114,118,[120][121][122][123][124][125][126][127][128].…”

Section: Design Of Cellulose With Microfluidicsmentioning

confidence: 99%

Cellulose through the Lens of Microfluidics: A Review

Moud

2022

Applied Biosciences

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Cellulose, a linear polysaccharide, is the most common and renewable biopolymer in nature. Because this natural polymer cannot be melted (heated) or dissolved (in typical organic solvents), making complicated structures from it necessitates specialized material processing design. In this review, we looked at the literature to see how cellulose in various shapes and forms has been utilized in conjunction with microfluidic chips, whether as a component of the chips, being processed by a chip, or providing characterization via chips. We utilized more than approximately 250 sources to compile this publication, and we sought to portray cellulose manufacturing utilizing a microfluidic system. The findings reveal that a variety of products, including elongated fibres, microcapsules, core–shell structures and particles, and 3D or 2D structured microfluidics-based devices, may be easily built utilizing the coupled topics of microfluidics and cellulose. This review is intended to provide a concise, visual, yet comprehensive depiction of current research on the topic of cellulose product design and understanding using microfluidics, including, but not limited to, paper-based microfluidics design and implications, and the emulsification/shape formation of cellulose inside the chips.

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Section: Design Of Cellulose With Microfluidicsmentioning

confidence: 99%

Cellulose through the Lens of Microfluidics: A Review

Moud

2022

Applied Biosciences

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“…The use of natural polymers in electrospinning systems have a strong relationship with their inherent capacity for binding cells, since they carry specific protein sequences (Bhardwaj and Kundu 2010). Collagen, alginate, chitosan, gelatin, casein, cellulose and its derivatives, silk fibroin, chitin and fibrinogen are examples of natural polymers that can be electrospun (Baker et al 2012;Luo et al 2018;Selvaraj et al 2018;Sizeland et al 2018;Dodero et al 2020;Arumugam et al 2021;Cui et al 2021;Jing et al 2021). In addition, these polymers can be used in blends with other polymers.…”

Section: Electrospinning Of Natural Polymersmentioning

confidence: 99%

“…Another alternative to enhance the properties of electrospun CA fibers is the use of blends with other natural polymers, such as chitin (Goetz et al 2016;Pereira et al 2020), chitosan (Phan et al 2019), silk fibroin (Arumugam et al 2021) and collagen (Lukanina et al 2018), gelatin (Farahani et al 2020). The results show that CA matrices loaded with other natural polymers have better mechanical properties, mostly smooth fibers without beads in nanometric scales and high stability in water, resulting to be materials of great interest for biometric applications or as filter media.…”

Section: Electrospinning Of Ca With Other Materialsmentioning

confidence: 99%

“…The reported results showed that the NFs had linear and cylindrical morphologies with a diameter ranging from 0.66 to 0.87 lm. The presence of the CA coating extinguished the initial release of ibuprofen, allowing the drug to be manipulated at a percentage of 90% during a tunable interval of 23.5 to 43.9 h. Arumugam et al (2021) recently investigated the biocompatible potential of electrospun NFs composed of SF/CA/Au-Ag for anticancer applications. As a result, the composite nanofiber exhibited excellent biological activity compared to other fibrous materials.…”

Section: Applications Of Electrospun Camentioning

confidence: 99%

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Cellulose-based electrospun nanofibers: a review

et al. 2021

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Cellulosic materials have gained a lot of attention in the last decades because of their abundancy, renewability and excellent physicochemical properties. Meanwhile, research on nanofibers has also been increasing with the aim of producing or modifying materials that can have a wide range of applications, such as tissue engineering, drug delivery, protective clothing and wound dressing. In order to produce these fibers, electrospinning is shown to be a promising and extensively used technique. Electrospun cellulosic fibers maintain the optimal characteristics of cellulose while improving its surface area to volume ratio and mechanical properties, in addition to the possibility of surface tailoring of bulk materials. However, there are several limitations related to the utilization of cellulose and most of its derivatives with the electrospinning technique. Poor solubility in most common solvents and inability to melt are major drawbacks. Thus, this review describes mostly recent research in which cellulose and its derivatives have been the feedstock for fabrication of nanofibers by electrospinning, exploring processing details and potential applications.

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“…17,18,36,37 Recently, inorganic materials such as metal oxides, zeolites, MOFs and noble metals were loaded into the nanobrous matrix to increase the delivery of anticancer drugs on the surface of the cancerous tissues. Gold-based nanomaterials with various shapes, including nanoparticles, [38][39][40] nanocages, 41,42 and nanorods [43][44][45] are incorporated into the different forms of drug delivery systems for targeted delivery and imaging in cancer therapy. Gold nanoparticles (Au NPs), due to their high stability, and easier synthesis were used to improve the attachment of cancerous cells and increase the therapeutic efficacy.…”

Section: Introductionmentioning

confidence: 99%