Electrospun fibers of poly(butylene succinate–co–dilinoleic succinate) and its blend with poly(glycerol sebacate) for soft tissue engineering applications

Liverani, Liliana; Piegat, Agnieszka; Niemczyk, Agata; Fray, Mirosława El; Boccaccını, Aldo R.

doi:10.1016/j.eurpolymj.2016.06.009

Cited by 50 publications

(46 citation statements)

References 38 publications

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“…Patntirapong and co-workers [173] promoted a sodium hydroxide hydrolysis of PBS/calcium phosphate composites and saw a concentration-dependent increase of vinculin and actin-reorganization-mediated adhesion of hMSC to be differentiated in osteogenic cells. Liverani and colleagues [174] also used PBS-based polymer electrospun with softer segments of dilinoleic succinate and/or polyglycerol sebacate, creating fully biobased biopolymers. These were then tested on mouse skeletal myoblast cell line C2C12 and on mouse postnatal cardiomyocytes.…”

Section: Bioscaffolds For Cell Cultivation In Vitromentioning

confidence: 99%

Recent Advances in Bioplastics: Application and Biodegradation

et al. 2020

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The success of oil-based plastics and the continued growth of production and utilisation can be attributed to their cost, durability, strength to weight ratio, and eight contributions to the ease of everyday life. However, their mainly single use, durability and recalcitrant nature have led to a substantial increase of plastics as a fraction of municipal solid waste. The need to substitute single use products that are not easy to collect has inspired a lot of research towards finding sustainable replacements for oil-based plastics. In addition, specific physicochemical, biological, and degradation properties of biodegradable polymers have made them attractive materials for biomedical applications. This review summarises the advances in drug delivery systems, specifically design of nanoparticles based on the biodegradable polymers. We also discuss the research performed in the area of biophotonics and challenges and opportunities brought by the design and application of biodegradable polymers in tissue engineering. We then discuss state-of-the-art research in the design and application of biodegradable polymers in packaging and emphasise the advances in smart packaging development. Finally, we provide an overview of the biodegradation of these polymers and composites in managed and unmanaged environments.

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Section: Bioscaffolds For Cell Cultivation In Vitromentioning

confidence: 99%

Recent Advances in Bioplastics: Application and Biodegradation

et al. 2020

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“…8,9 Therefore, just a few reports present the fabrication of elastomeric scaffolds obtained by electrospinning, with the need of be processed by blends or sacricial polymers. 10,11 To overcome these drawbacks, a big deal of research has been focused in the development of new thermoplastic elastomers (TPE) as they are the most versatile family of elastomeric materials, thanks to having many of the physical properties of crosslinked elastomers (rubbers) and being processed as thermoplastics. TPEs are (multi)block copolymers composed of thermodynamically incompatible segments built up from rigid (hard) thermoplastic components and so elastomeric components.…”

Section: Introductionmentioning

confidence: 99%

Enzymatic synthesis of an electrospinnable poly(butylene succinate-co-dilinoleic succinate) thermoplastic elastomer

Sonseca

Fray

2017

RSC Adv.

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“…The recent three years brought a few more publications from the scope of PGS electrospinning, with a focus on applications for soft tissue engineering and nerve tissue engineering [19][20][21][22][23][24][25], and a few more about the electrospinning process with PGS as one of the components [26][27][28][29][30][31]. None of them, however, were devoted to investigations of electrospinning of PLA-PGS blends.…”

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confidence: 99%

Poly(Glycerol Sebacate)–Poly(l-Lactide) Nonwovens. Towards Attractive Electrospun Material for Tissue Engineering

2019

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Two types of poly(glycerol sebacate) (PGS) prepolymers were synthesized and electrospun with poly(l-lactic acid) (PLA), resulting in bicomponent nonwovens. The obtained materials were pre-heated in a vacuum, at different times, to crosslink PGS and investigate morphological and structural dependencies in that polymeric, electrospun system. As both PGS and PLA are sensitive to pre-heating (crosslinking) conditions, research concerns both components. More interest is focused on the properties of PGS, considering further research for mechanical properties and subsequent experiments with PGS synthesis. Electrospinning of PGS blended with PLA does not bring difficulties, but obtaining elastomeric properties of nonwovens is problematic. Even though PGS has many potential advantages over other polyesters when soft tissue engineering is considered, its full utilization via the electrospinning process is much harder in practice. Further investigations are ongoing, especially with the promising PGS prepolymer with a higher esterification degree and its variations.

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Electrospun fibers of poly(butylene succinate–co–dilinoleic succinate) and its blend with poly(glycerol sebacate) for soft tissue engineering applications

Cited by 50 publications

References 38 publications

Recent Advances in Bioplastics: Application and Biodegradation

Recent Advances in Bioplastics: Application and Biodegradation

Enzymatic synthesis of an electrospinnable poly(butylene succinate-co-dilinoleic succinate) thermoplastic elastomer

Poly(Glycerol Sebacate)–Poly(l-Lactide) Nonwovens. Towards Attractive Electrospun Material for Tissue Engineering

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