Electrospun hypromellose-based hydrophilic composites for rapid dissolution of poorly water-soluble drug

Wang, Qing; Yu, Deng‐Guang; Zhang, Lingling; Liu, Xinkuan; Deng, Yangchao; Zhao, Min

doi:10.1016/j.carbpol.2017.06.075

Cited by 159 publications

(93 citation statements)

References 41 publications

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“…Three different polymers (HPMC, PVPK30 and PVPVA64) and three different drug loadings (20,30, and 40%) were screened by SNES. The best composition was chosen based on the in vitro dissolution tests.…”

Section: Resultsmentioning

confidence: 99%

“…Although the electrospinning (ES) is fast developing with appearance of tri-axial, coaxial, side-by-side and their combination processes [19][20][21][22] the most common and facile ES equipment is the single needle apparatus [23,24]. The single needle electrospinning (SNES) applies a syringe filled with a polymerdrug containing solution, which is then forced through a nozzle attached to high voltage.…”

mentioning

confidence: 99%

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Scaled-up preparation of drug-loaded electrospun polymer fibres and investigation of their continuous processing to tablet form

Szabó

Démuth

Nagy

et al. 2018

Express Polym. Lett.

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Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

Scaled-up preparation of drug-loaded electrospun polymer fibres and investigation of their continuous processing to tablet form

Szabó

Démuth

Nagy

et al. 2018

Express Polym. Lett.

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“…Certainly, they are still some other complicated issues such as final applications of the electrosprayed particles. For examples, these particles can be easily exploited for providing sustained release, fast release and biphasic release [22][23][24]; the drugs can be both therapeutic ingredients and also agents for detection [25,26]; and the polymeric matrix can be water soluble, degradable or insoluble [27,28]. As for a complicated engineering issue, it has at least three layers of meaning.…”

Section: Complicated Issues For An Example Application -Electrosmentioning

confidence: 99%

Complicated Engineering Issues about Electrospraying - A Vivid Lesson for Engineering Education in Higher School

Wu¹,

Huang²,

Sun³

et al. 2017

Proceedings of the International Conference on Education Innovation and Social Science (ICEISS 2017)

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Abstract-The capability of finding and resolving complicated engineering issues is very important for the college students to begin their career. In high school, teachers should take advantage of advanced technologies in two ways. One is to transfer the knowledge and practice experiences to the students and the other is to share with them how to find and resolve the complicated issues. In this paper, with electrospraying as an objective, several complicated issues are put forward. Electrospraying is a simple but very complicated engineering process. When it is exploited to create medicated composite for drug sustained release, complicated issues occur not only at the selections of raw materials, suitable working processes and key parameters, but also at the systematic designs of final functional nanomaterials and smooth implementation of working processes. Advanced technologies can be vivid teaching materials for the students to learn how to refine and resolve complex engineering issues, and thus to foster their practice interests, to improve their innovative and engineering capabilities.

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“…This nanotechnology has a series of unique properties making it very popular in the present scientific research fields and also in the potential industrial applications [2][3][4][5][6][7]. These properties include a very simple process (one-step), a straight forward manner to create solid nanofiber, very cost, and excellent properties of the resultant nanofiber non-woven mat [8][9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Teaching Materials for Engineering Education in High School from the Increase of Working Fluids in Electrospinning

Li¹,

Zhu²,

Wang³

et al. 2018

Proceedings of the 2018 2nd International Conference on Management, Education and Social Science (ICMESS 2018)

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Abstract-Scientific innovation is often reflected in the engineering processes. On the contrary, the engineering processes hidden in advanced technologies can provide many vivid teaching materials for effective innovation and engineering educations to the college students in high school. In this paper, we conclude the advancement of electrospinning processes, which is fast developed from one-fluid blending process two decades before to two-fluid coaxial electrospinning, and now develops three-fluid tri-axial electrospinning. The increase of working fluids in electrospinning is useful for college students to provoke their interests in advanced nanotechnologies. Meanwhile, the increase of working fluids in electrospinning is also excellent teaching materials for the students to build linkages between their previous knowledge and new technologies, so deepening their comprehensions on them. What is more, the increase of working fluids in electrospinning is excellent teaching materials for the students to learn how to implement innovations all by themselves， such as engineering design innovation, analogical innovation, and innovation of analytical methods.

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Electrospun hypromellose-based hydrophilic composites for rapid dissolution of poorly water-soluble drug

Cited by 159 publications

References 41 publications

Scaled-up preparation of drug-loaded electrospun polymer fibres and investigation of their continuous processing to tablet form

Scaled-up preparation of drug-loaded electrospun polymer fibres and investigation of their continuous processing to tablet form

Complicated Engineering Issues about Electrospraying - A Vivid Lesson for Engineering Education in Higher School

Teaching Materials for Engineering Education in High School from the Increase of Working Fluids in Electrospinning

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