Electrospun manganese (III) oxide nanofiber based electrochemical DNA-nanobiosensor for zeptomolar detection of dengue consensus primer

Tripathy, Suryasnata; Vanjari, Siva Rama Krishna; Singh, Vikrant; Swaminathan, Sathyamangalam; Singh, Shiv Govind

doi:10.1016/j.bios.2016.12.008

Cited by 90 publications

(33 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The immobilization technique of a capture probe can influence biosensor efficiency. For instance, several studies are devoted to the development of DNA/RNA biosensor platforms modified with metals or their oxides to increase the electroactive surface of the sensor, which provides stable and sensitive electrochemical detection of the DENV of various serotypes [66,81]. The presence of metals or their oxides on the electrode surface contributes to the biocompatibility and target specificity with DNA molecules [82].…”

Section: Dna and Rna Biosensors For Denv Diagnosticmentioning

confidence: 99%

Label-Free Electrochemical Biosensors for the Determination of Flaviviruses: Dengue, Zika, and Japanese Encephalitis

Khristunova

Dorozhko

Короткова

et al. 2020

Sensors

View full text Add to dashboard Cite

A highly effective way to improve prognosis of viral infectious diseases and to determine the outcome of infection is early, fast, simple, and efficient diagnosis of viral pathogens in biological fluids. Among a wide range of viral pathogens, Flaviviruses attract a special attention. Flavivirus genus includes more than 70 viruses, the most familiar being dengue virus (DENV), Zika virus (ZIKV), and Japanese encephalitis virus (JEV). Haemorrhagic and encephalitis diseases are the most common severe consequences of flaviviral infection. Currently, increasing attention is being paid to the development of electrochemical immunological methods for the determination of Flaviviruses. This review critically compares and evaluates recent research progress in electrochemical biosensing of DENV, ZIKV, and JEV without labelling. Specific attention is paid to comparison of detection strategies, electrode materials, and analytical characteristics. The potential of so far developed biosensors is discussed together with an outlook for further development in this field.

show abstract

Section: Dna and Rna Biosensors For Denv Diagnosticmentioning

confidence: 99%

Label-Free Electrochemical Biosensors for the Determination of Flaviviruses: Dengue, Zika, and Japanese Encephalitis

Khristunova

Dorozhko

Короткова

et al. 2020

Sensors

View full text Add to dashboard Cite

show abstract

“…Figure 4(A) represents the cyclic voltammograms, where peak-to-peak voltage difference (ΔE) is 98 mV, and peak current has decreased from GCE (64.5 μA) to GCE/CoZnONF (42.75 μA) which indicates the decreased rate of electron transfer at the GCE/CoZnONF surface. This is a quasi-reversible behavior that represents the semiconductive nature of NF [62]. EIS was also used to investigate the effects of surface modification, antibody immobilization, and the electron transfer properties shown in Figure 4(B).…”

Section: Electrochemical Studies Of Antibody Immobilized Bioelectrodementioning

confidence: 99%

A Facile, Sensitive and Rapid Sensing Platform Based on CoZnO for Detection of Fipronil; an Environmental Toxin

et al. 2020

Self Cite

View full text Add to dashboard Cite

A sensitive detection of extremely toxic phenylpyrazole insecticide, ‘Fipronil’ is presented. Currently, the advancement of approaches for the detection of insecticides at low concentrations with less time is important for environmental safety assurance. Considering this fact, an effort has been made to develop an electrospun CoZnO nanofiber (NF) based label‐free electrochemical system for the detection of fipronil. The CoZnO NF were characterized using different techniques including field emission scanning electron microscopy (FE‐SEM), Energy Dispersive X‐Ray Analysis (EDX), X‐ray diffraction (XRD), Fourier‐transform infrared spectroscopy (FTIR), and Raman Spectroscopy. Based on the experimental results, the proposed platform displayed a linear response for fipronil in the attogram/mL range despite the multiple interfering agents. The sensitivity of the device was found to be 3.99 KΩ (g/ml)−1 cm−2. Limit of detection (LOD) and limit of quantification (LOQ) were calculated and found to be 112 ag mL−1 and 340 ag mL−1 respectively. Further, this proposed sensor will be implemented in the fields for the rapid and proficient detection of the real samples.

show abstract

“…Subsequently, the sample containing target DNA was added, and electrochemical responses were measured against a standard calomel reference electrode. The study revealed that nanoscale genosensor successfully detected dengue DNA and LOD of the sensor was found to be 120 zeptomoles [37]. Rashid et al worked on electrochemical genosensor that is developed on screen-printed gold electrode modified with silicon nanowires (SiNWs).…”

Section: Detection Of Dengue Genomementioning

confidence: 99%

New Tools for Dengue Diagnostics

Kumari¹,

Deva²,

Lal³

et al. 2019

Dengue Fever - A Resilient Threat in the Face of Innovation

View full text Add to dashboard Cite

Dengue caused by four antigenically distinct serotype remains a serious health concern around the world, particularly in the tropical areas. Clinical signs and symptoms of this disease are indistinguishable from other infectious disease; therefore, laboratory diagnosis is very crucial for confirming the disease that will be useful for the patient's management. In laboratory, dengue can be confirmed using cell culture, RNA detection, and serological detection based on ELISA and immunochromatographic test. However, each of these methods has certain practical limitations. Therefore, researchers from all over the world have been working to address these limitations. In this chapter, we will highlight the current research toward the development of novel point-of-care test for the diagnosis of dengue in acute and convalescent phase.

show abstract

Electrospun manganese (III) oxide nanofiber based electrochemical DNA-nanobiosensor for zeptomolar detection of dengue consensus primer

Cited by 90 publications

References 65 publications

Label-Free Electrochemical Biosensors for the Determination of Flaviviruses: Dengue, Zika, and Japanese Encephalitis

Label-Free Electrochemical Biosensors for the Determination of Flaviviruses: Dengue, Zika, and Japanese Encephalitis

A Facile, Sensitive and Rapid Sensing Platform Based on CoZnO for Detection of Fipronil; an Environmental Toxin

New Tools for Dengue Diagnostics

Contact Info

Product

Resources

About