Electrospun nanofibers for microfluidic analytical systems

A review of electrospinning manipulation techniques to direct fiber deposition and maximize pore size

“…A control system must be used to increase the accuracy of the electrospinning process. There are several methods that can be used to manipulate the created nanofibers described in previous studies, such as electric field manipulation, alternating current (AC) electrospinning, and magnetic field manipulation [80,[96][97][98][99][100][101][102][103][104][105][106][107][108][109][110][111][112].…”

“…This technique was used by Cho et al to form an electrospun nanofibrous filter within microchannels using gold electrodes embedded beneath the sides of the channels. This aligned the fibers across the channel to form a filter [101].…”

Integrative Utilization of Microenvironments, Biomaterials and Computational Techniques for Advanced Tissue Engineering

“…Biomaterials can also be formed in specific formats using microfluidic devices, for example, biomaterials with stiffness gradients have been formed within microfluidic systems [84]. Moreover, multiple layers of biomaterials with specific alignment features have been created which are applicable for a controllable study of the biomaterial effects in inducing cellular responses on a single chip [85,86]. Numerous methods have also been used to control and manipulate the microenvironment of cells and tissues by perturbing their chemical, physical, electrical, and optical conditions all employing the advantages of microfluidic devices as powerful tools for a precise control over cells and tissues in micron scales.…”

Microfluidizer Technique for Improving Microfiber Properties Incorporated Into Edible and Biodegradable Films

“…Microfluidic process has become an attractive technology for numerous applications [Atalay et al, 2011;Cho et al, 2011;Napoli et al, 2011;Schirhagl et al, 2010;Thompson et al, 2010;Zhang et al, 2011] due to unique characteristics, such as: i) efficient and rapid mix leading to rapid chemical reaction; ii) homogeneous reaction environments; iii) continuously varied reaction conditions and iv) precise time intervals to add reagents during reaction [deMello, 2006;DeMello & DeMello, 2004]. Therefore, the application of the microfluidic devices improves the control of the synthesis parameters and thus the nanoparticle sizes and properties [Il Park et al, 2010] and optimizes the miniaturization of the microstructures.…”