Electrospun nanofibers of poly (acrylonitrile-co-itaconic acid)/silver and polyacrylonitrile/silver: In situ preparation, characterization, and antimicrobial activity

Abstract

In this study, it was aimed to prepare silver nanoparticles by reduction of silver salt (AgNO3) in situ by means of only synthesized polyacrylonitrile (PAN) and poly(acrylonitrile-co-itaconic acid) (P(AN-co-IA)) polymers, and N,N dimethylformamide (DMF). Thereafter, PAN/Ag and P(AN-co-IA)/Ag nanofibers were prepared via electrospinning. Spectroscopic and morphologic characterizations, electrical and thermal features, and antimicrobial activities of the prepared nanofibers against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans were carried out in detail. It was observed that P(AN-co-IA) was much more effective than PAN on the reduction of AgNO3 and formation of silver nanoparticles. Silver nanoparticles and also itaconic acid contributed to decrease the cyclization temperature of PAN by generating sharp exothermic peaks. In addition, electrical conductivity of the nanofibers increased dramatically from E−13 to E−4 related to the presence of silver nanoparticles. Furthermore, incorporation of silver nanoparticles to the nanofiber membranes let bactericidal/fungicidal activities, which started at 6–24 h and continued for up to 168 h, against S. aureus, E. coli, P. aeruginosa, and C. albicans. The prepared silver containing nanofibers can be regarded as good candidates for potential use in the biomedical and pharmaceutical applications.

Cosmetotextiles and Evaluation of Their Performance

“…It was shown that all nanocarriers prolonged vitamin E release but best by solid lipid nanoparticles from cosmetototextile products for use in skin cell repair and restoration for ocular area. Due to having large surface area, very small diameters, high loading efficiency and sustained release properties, electrospun nanofibers are one of the promising cosmetotextiles in recent years 34, 35 . In a study, electrospun poly (vinyl alcohol)/chitosan nanofibers incorporated with a combination of polyphenol-rich-herbal extracts was developed for use in facial acne treatment.…”

Silver-loaded poly(vinyl alcohol)/polycaprolactone polymer scaffold as a biocompatible antibacterial system

“…Nanofibers mats can be prepared by electrospinning method and applied in several fields including filtration 17 , drug delivery 5 , nanosensors 18 and wound dressing as well 1 , 5 . Electrospinning enables the production of fibers from a wide range of polymers 19 , 20 or polymers blends with antibacterial agents 1 , 5 while allowing control over the properties of the nanofiber mat, such as the fiber’s size distribution, porosity, or mat thickness 19 .…”

Rose bengal-integrated electrospun polyacrylonitrile nanofibers for photodynamic inactivation of bacteria

“…[20][21][22][23] PAN can be effectively used in nanocomposites and carbon bre production, and can also be used in a copolymer form for bre productions. 24 To produce antimicrobial electrospun nanobers, antimicrobial components can be integrated into nanobers during the electrospinning procedure. The antimicrobial effects were observed from electrospun nanobers integrated with silver nanoparticles (Ag NPs), 25 chitosan-silver NPs, 16 graphene oxide, 26 cinnamaldehyde, 27 antimicrobial peptides, 28 etc.…”

“…20–23 PAN can be effectively used in nanocomposites and carbon fibre production, and can also be used in a copolymer form for fibre productions. 24…”