Electrospun silver nanoparticles/curcumin-loaded nanohybrids for Photodynamic Therapy

Braga, Thais Lazzarotto; de Souza Rossin, Ariane Regina; Fernandes, Juliana Aparecida; de Souza Bonfim de Mendonça, Patrícia; de Castro-Hoshino, Lidiane Vizioli; Baesso, Mauro Luciano; de Freitas, Camila Fabiano; Radovanovic, Eduardo; Caetano, Wilker

doi:10.1016/j.apmt.2024.102073

Cited by 3 publications

(2 citation statements)

References 52 publications

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“…has very small relationship with these electrospinning apparatus parts. The physical properties of the working polymeric fluids always play a dominant role in determining the shapes of final EHDA products (Braga et al, 2024;Brimo et al, 2023). For ensuring the formations of linear nanofibers, the molecular weight and concentration of the filamentforming polymers must be over their critical values to ensure an enough physical entanglements in the working fluids (Duan et al, 2024).…”

Section: The Developments Of Ehda On Creating Shapesmentioning

confidence: 99%

Engineered shapes using electrohydrodynamic atomization for an improved drug delivery

Yu,

Gong,

Zhou

et al. 2024

WIREs Nanomed Nanobiotechnol

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The shapes of micro‐ and nano‐products have profound influences on their functional performances, which has not received sufficient attention during the past several decades. Electrohydrodynamic atomization (EHDA) techniques, mainly include electrospinning and electrospraying, are facile in manipulate their products' shapes. In this review, the shapes generated using EHDA for modifying drug release profiles are reviewed. These shapes include linear nanofibers, round micro‐/nano‐particles, and beads‐on‐a‐string hybrids. They can be further divided into different kinds of sub‐shapes, and can be explored for providing the desired pulsatile release, sustained release, biphasic release, delayed release, and pH‐sensitive release. Additionally, the shapes resulted from the organizations of electrospun nanofibers are discussed for drug delivery, and the shapes and inner structures can be considered together for developing novel drug delivery systems. In future, the shapes and the related shape–performance relationships at nanoscale, besides the size, inner structure and the related structure–performance relationships, would further play their important roles in promoting the further developments of drug delivery field.This article is categorized under: Therapeutic Approaches and Drug Discovery > Emerging Technologies

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Section: The Developments Of Ehda On Creating Shapesmentioning

confidence: 99%

Engineered shapes using electrohydrodynamic atomization for an improved drug delivery

Yu,

Gong,

Zhou

et al. 2024

WIREs Nanomed Nanobiotechnol

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“…12–14 Moreover, the nano-network structure of electrospun nanofibrous membranes closely resembles the natural extracellular matrix (ECM) of skin, making them promising candidates for wound treatment. 15–17 Additionally, electrospinning has evolved from single-fluid 18,19 to side-by-side 20,21 or coaxial, 22,23 triaxial 24,25 or even other multi-fluid derived structures including core–shell, 22 porous, 26 Janus 27,28 and even more complex and fine structures. 29,30 This offers a straightforward and practical method for utilizing a wide range of raw or modified materials, providing control over the nanofiber morphology and structure.…”

Section: Introductionmentioning

confidence: 99%

Electrospun organic/inorganic hybrid nanofibers for accelerating wound healing: a review

Yan,

Qian,

Haghayegh

et al. 2024

J. Mater. Chem. B

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Hydrogen‐Bonded Organic Frameworks as a Carrier for Nanodrugs with Host–Guest Interaction for Smart Wound Dressing Applications

Moeinipour,

Afkhami,

Madrakian

2024

ChemistrySelect

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This study introduces surface modification to conventional dressings utilizing adducts of a hydrogen‐bonded organic framework (HOF) with curcumin, curcumin–silver, curcumin‐zinc oxide nanoparticles, and citric acid drugs. Accordingly, eight HOF‐AMs and dressings modified with them were studied. The synthesized structures underwent characterization using various methods, including IR, 1H NMR, XRD, FE‐SEM, and EDX. FE‐SEM results show that the hexagonal morphology is maintained along with the crystal growth in the form of hexagonal tubes. In order to confirm the nanoscale nature of the structures, TEM analysis was conducted specifically for curcumin‐Ag nanoparticles and curcumin–ZnO nanoparticles which confirms the particle size smaller than 50 nm. Knowing the sensitivity of the release of the incorporated substances to temperature and pH, the controlled release of the drugs at two different temperatures (37 °C and 40 °C) and pH levels of 5.5, 7.4, and 9 at the modified dressings was investigated. Investigating the release of HOF‐AMs particles and modified dressings indicates that these products in both cases provide the possibility of drug release in alkaline and acidic pHs. Also, the results showed that increasing the temperature increases the release of curcumin particles in all its types. The modified dressings showed a loading capacity of more than 50 mg g−1.

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Electrospun silver nanoparticles/curcumin-loaded nanohybrids for Photodynamic Therapy

Cited by 3 publications

References 52 publications

Engineered shapes using electrohydrodynamic atomization for an improved drug delivery

Engineered shapes using electrohydrodynamic atomization for an improved drug delivery

Electrospun organic/inorganic hybrid nanofibers for accelerating wound healing: a review

Hydrogen‐Bonded Organic Frameworks as a Carrier for Nanodrugs with Host–Guest Interaction for Smart Wound Dressing Applications

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