“…The NeuroElectric Therapy (NET) Device offers a promising non-pharmacological approach for treatment of persons with OUD but has not yet undergone rigorous clinical efficacy evaluation. Similar earlier-generation devices have been studied extensively under open-label, non-controlled conditions, and exclusively in the inpatient setting, as a possible monotherapy for medication-free detoxification from chronic substance use [ [31] , [32] , [33] , [34] ]. In April 2009, the NET Device received CE-mark as a Class IIa medical device.…”