Elektronenoptische Untersuchungen des Pankreas unter normalen und abnormen Stoffwechsellagen

Nordmann, Melanie; Wolf, Eugene M.

doi:10.1007/bf00959548

Cited by 12 publications

(1 citation statement)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The present experimental results do not confirm the hypothesis of the selective destruction by CoC12 of the pancreatic A-cells (van Campenhout and Comelis, 1951;Goldner et al, 1954;Creutzfeldt, 1954;Holt, 1954;Fodden, 1956;Rode, 1960;Vaissman, 1962). Another factor arguing against this hypothesis is that following CoC12 administration only Part of the A-cells (about 30 %) appear vacuolized (Goldner et al, 1954;Hultquist, 1959b;Hultquist, 1961;Lacy and Cardeza, 1959;Nordmann and Wolf, 1960). Likewise, the glucagon vaiues taken from blood plasma do not show, in these conditions, a decrease of glucagon concentration which should appear in the case of a toxic action of CoC12 upon A-cells (Lochner, 1964;.…”

Section: Electron Microscopy Observationsmentioning

confidence: 99%

Effect of CoCl₂on the Cells of Endocrine Pancreas in the Snake (Natrix n. natrix)

Calugareanu¹

1970

Horm Metab Res

View full text Add to dashboard Cite

1. Administration of CoCI2 induces a discontinuous three-phase hyperglycernia in the snake (n. Natrix natrix). 2. Initial hypcrglycemia seems to be of adrenalinic origin, a fact demonstrated by treatment with ergotamine and reserpine resulting in no or only a negligible hyperglycemia, respectively. 3. The decrease of hyperglycernia in the interval from 6 to 9 hours is due to a hyperinsulinemia of B-pancreatic origin, a result of the property of Co of crystallizing insulin. This fact is evidenced electron microscopically by the growth of the relationship between crystallized and non-crystallized granules. 4. Finally, compensatory hyperglycemia IS ot A2-pancreauc origin, illustrated both by increased secretion indices of A2 ceHs, such as partial degranulation of the cells, as weH as by increased proteinic synthesis indices, Le. ergastoplasm development, a multitude of ribosomes, occurrence of granules of smaH dimensions.

show abstract

Section: Electron Microscopy Observationsmentioning

confidence: 99%

Effect of CoCl₂on the Cells of Endocrine Pancreas in the Snake (Natrix n. natrix)

Calugareanu¹

1970

Horm Metab Res

View full text Add to dashboard Cite

show abstract

Vergleichende Morphologie der Langerhans’schen Inseln der Wirbeltiere

Kern¹

1971

Insulin

View full text Add to dashboard Cite

Elektronenmikroskopische Differenzierung verschiedener Inselzelltypen im Pankreas normaler Albinoratten

Faller

1969

Z. Zellforsch.

View full text Add to dashboard Cite

Elektronenoptische Untersuchungen des Pankreas unter normalen und abnormen Stoffwechsellagen

Cited by 12 publications

References 3 publications

Effect of CoCl₂on the Cells of Endocrine Pancreas in the Snake (Natrix n. natrix)

Effect of CoCl₂on the Cells of Endocrine Pancreas in the Snake (Natrix n. natrix)

Vergleichende Morphologie der Langerhans’schen Inseln der Wirbeltiere

Elektronenmikroskopische Differenzierung verschiedener Inselzelltypen im Pankreas normaler Albinoratten

Contact Info

Product

Resources

About

Elektronenoptische Untersuchungen des Pankreas unter normalen und abnormen Stoffwechsellagen

Cited by 12 publications

References 3 publications

Effect of CoCl2on the Cells of Endocrine Pancreas in the Snake (Natrix n. natrix)

Effect of CoCl2on the Cells of Endocrine Pancreas in the Snake (Natrix n. natrix)

Vergleichende Morphologie der Langerhans’schen Inseln der Wirbeltiere

Elektronenmikroskopische Differenzierung verschiedener Inselzelltypen im Pankreas normaler Albinoratten

Contact Info

Product

Resources

About

Effect of CoCl₂on the Cells of Endocrine Pancreas in the Snake (Natrix n. natrix)

Effect of CoCl₂on the Cells of Endocrine Pancreas in the Snake (Natrix n. natrix)