Elemental Silver Nanoparticles: Biosynthesis and Bio Applications

Михайлов, О. В.; Михайлова, Е. О.

doi:10.3390/ma12193177

Cited by 40 publications

(34 citation statements)

References 237 publications

(467 reference statements)

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“…8,9 Additionally, these nanoparticles have turned out to be essential for their excellent chemical and thermal stability. 10 ZnO NPs have remarkable fluorescence in cells so that they are biomarkers in relevant clinical and biomedical applications. 11 They have emerged as a promising and innovative technique for the efficient delivery of drugs in treating some diseases by specific targeting.…”

Section: Introductionmentioning

confidence: 99%

“… 8 , 9 Additionally, these nanoparticles have turned out to be essential for their excellent chemical and thermal stability. 10 …”

Section: Introductionmentioning

confidence: 99%

“…It is used in cosmetics, pharmaceuticals, and the plant is utilized as a spice (seeds) and a vegetable (tuber). 10 In the last years, the water extraction process of the fennel seeds was optimized to produce extracts containing more valuable bioactive substances. The yield of polyphenols, flavonoids, and the total dry extract are higher when using water as a solvent.…”

Section: Introductionmentioning

confidence: 99%

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<p>Therapeutic Potential Assessment of Green Synthesized Zinc Oxide Nanoparticles Derived from Fennel Seeds Extract</p>

AlSalhi¹,

Devanesan²,

Al-Qahtani³

et al. 2020

IJN

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To study the cytotoxic evaluation, antimicrobial and confocal analysis of zinc oxide nanoparticles (ZnO NPs) obtained from a novel plant product fennel (Foeniculum vulgare Mill.) seed extract (FSE). Methods: ZnO NPs were analyzed using UV-Vis spectroscopy, XRD, FTIR, TEM and EDX techniques. The MTT cell cytotoxicity assay measured the proliferation and survival of MCF-7 cells treated at different concentrations of FSE-derived ZnO NPs. The antimicrobial activity towards pathogenic bacteria and yeast strains was investigated. Results: The UV-Vis spectra showed two peaks at 438 nm and 446 nm, confirming nanoparticle formation. The SEM morphology results showed porous ranging from 23-51 nm. The antitumor activity value (IC 50) was at 50 µg/mL and 100 µg/mL. Besides, morphological changes of MCF-7, cells treated at different concentrations of FSE of ZnO NPs were observed in cell cultures transfected with a transient pCMV6-XL4-GFP-expressing vector containing C-terminal domain GFP-tagged proteins, which resulted in an apoptotic effect. Antimicrobial IZ ranged up No Inhibition to 18.00 ± 0.4. The IZ revealed at the highest concentration was E. faecium VRE and yeast Cryptococcus sp. (18.00 ± 0.4. mm), followed by S. aureus (17.00 ± 0.2 mm) and P. aeruginosa and the yeast C. parapsilosis (16 ± 0.4 mm). The IZ was equal to that caused by the nystatin to Cryptococcus sp., which was significantly highest than ampicillin treatments of S. aureus, P. aeruginosa, C. albicans, and C. parapsilosis. The MIC value of the FSE-derived ZnO NPs tested against E.faecium and C. albicans was 6.00 µg/mL (E. faecium and C. albicans). It was 32.00 µg/mL (S. aureus, S. typhimurium and Cryptococcus sp.), 64.00 µg/mL (P. aeruginosa), and 128 µg/mL (C. parapsilosis). Conclusion: As far as it is to our knowledge, this study established, for the first time, the biological activities of biosynthesized ZnO NPs from FSE and their synergistic therapeutic potential.

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Section: Introductionmentioning

confidence: 99%

“… 8 , 9 Additionally, these nanoparticles have turned out to be essential for their excellent chemical and thermal stability. 10 …”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

<p>Therapeutic Potential Assessment of Green Synthesized Zinc Oxide Nanoparticles Derived from Fennel Seeds Extract</p>

AlSalhi¹,

Devanesan²,

Al-Qahtani³

et al. 2020

IJN

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“…Several noble nanomaterials such as silver, gold, mercury, platinum, copper and zinc are employed in the biological, agricultural and biomedical fields (Arvizo et al 2012; Johnson alias Antonysamy et al, 2017). Ag NPs have been well-known in manmade activities since ancient time (Mikhailov et al, 2019). The crystalline nature and morphology of NPs play pivotal role in the parameter of their chemical and physical traits (Coe et al, 2002;Mittal et al, 2016;Rizwan et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Characterization, and Antimicrobial Properties of Sparfloxacin-Mediated Noble Metal Nanoparticles

Nisar¹,

Khan²,

Gul³

et al. 2020

J Pure Appl Microbiol

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The aim of the current research finding was to synthesize, characterize and antibacterial evaluation of sparfloxacin-mediated noble metal nanoparticles. Noble metal [silver (Ag), and gold (Au)] nanoparticles (NPs), mediated with fluoroquinolone, an anti-bacterial drug [Sparfloxacin, (Sp)], was synthesized by a facile and convenient procedure. Formulated Ag-Sp NPs, and Au-Sp NPs exhibited stability against variation in pH, NaCl solution, temperature, and time. The structural topographies of Ag-Sp, and Au-Sp NPs were determined by fourier transform infrared spectroscopy (FTIR), UV-visible spectroscopy (UV-Vis), scanning electron microscopy (SEM) atomic force microscopy (AFM), and energy dispersive X-ray (EDX). UV-Vis revealed the formulation of NPs by showing typical surface Plasmon absorption maxima at 410 nm for Ag-Sp NPs and 555 nm for Au-Sp NPs. The AFM and SEM analysis ascertained stable mono dispersed Ag-Sp NPs and Au-Sp NPs in the size range of 40-50 nm, and 70-80 nm, respectively. Ag-Sp, and Au-Sp NPs exhibited antibacterial traits against Bacillus subtilis, Staphylococcus aureus, and Klebsiella pneumonia, showing a zone of inhibition (ZOI) ranging from 20±0.98 mm to 24±0.94 mm (Ag-Sp NPs), and 22±0.79 mm to 26±0.92 mm (Au-Sp NPs) at dose of 3 mg/mL.

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“…It was also demonstrated that a much greater variety of nanoparticle assemblies could be produced by cells along the "bottom-up" approach (Zhang et al, 2011;Woehl et al, 2014;Sánchez-López et al, 2020) (Figure 1). Observations clearly show that nanocrystals can nucleate from an aqueous solution via a threestep mechanism: spinodal decomposition, clusterization, and nanocrystallization (Luo et al, 2017;Tan et al, 2017;Xie et al, 2017;Liao et al, 2019;Mikhailov and Mikhailova, 2019;Wang et al, 2019). The amorphous clusters of zero-valent atoms (up to 1-2 nm) are direct precursors of the bigger crystalline nanoparticles (Malis et al, 2011;Wan et al, 2013;Loh et al, 2017;Singh et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Detection of Microorganisms in Low-Temperature Water Environments by in situ Generation of Biogenic Nanoparticles

Складнев

Vasilyeva

Berestovskaya

et al. 2020

Front. Astron. Space Sci.

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A new nanobiotechnological approach for the detection of extraterrestrial Earth-like biological forms is proposed. The approach is based on the ability of microbial cells to reduce artificially added cations with the generation of crystalline nanoparticles (NPs) from zero-valent atoms. The method is named DBNG (Detection of Biogenic Nanoparticles Generation). The subglacial low-temperature oligotrophic Lake Untersee in Antarctica was used as a model of putative extraterrestrial water environments inhabited by Earth-like type microorganisms. The DBNG protocol for the comparative study of microbial communities of low-temperature oligotrophic environments was optimized on the base of experiments with the pure culture of psychroactive bacterium Cryobacterium sp. 1639 isolated earlier from Lake Untersee. The formation of silver nanoparticles (Ag°NPs) has been conducted in natural water samples of three horizons at low temperature (+5°C), which was in the temperature range registered in the Lake Untersee. The generation of biogenic Ag°NPs was detected only at the presence of indigenous microorganisms in all studied samples. No Ag°NPs generation was observed in the lake water samples artificially free of cells or exposed to pasteurization (two types of controls). The miniature microfluidic chip for an automated version of the device, based on using different analytical methods for recording in situ-formed biogenic nanoparticles, is proposed. The device allows the detection of the biological objects directly at the sampling site.

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Elemental Silver Nanoparticles: Biosynthesis and Bio Applications

Cited by 40 publications

References 237 publications

<p>Therapeutic Potential Assessment of Green Synthesized Zinc Oxide Nanoparticles Derived from Fennel Seeds Extract</p>

<p>Therapeutic Potential Assessment of Green Synthesized Zinc Oxide Nanoparticles Derived from Fennel Seeds Extract</p>

Synthesis, Characterization, and Antimicrobial Properties of Sparfloxacin-Mediated Noble Metal Nanoparticles

Detection of Microorganisms in Low-Temperature Water Environments by in situ Generation of Biogenic Nanoparticles

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