“…In contrast, purified toxin B does not cause fluid secretion, inflammatory infiltrate, or morphologic damage in rabbit or hamster intestine (1)(2)(3). The effects of toxin A are not accompanied by elevation of adenylate cyclase (4), indicating that its mechanism of action differs from, cholera toxin and Escherichia coli heat labile enterotoxin, which stimulate intestinal adenylate cyclase and cause fluid secretion without producing an inflammatory infiltrate (5,6).…”