Elevated sleep and waking heart rates in anxious depressions

Abramson, Lauren; Keshavan, M.S.; Sitaram, Natraj

doi:10.1016/0006-3223(89)90070-x

Cited by 7 publications

(2 citation statements)

References 10 publications

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“…In a Finnish study, symptoms of coronary heart disease were also related (14). A recent finding of elevated sleep and waking heart rates in anxious depression is also of interest (15). Panic syndrome and depression were associated with insomnia in a Swiss population-based study (16).…”

Section: Discussionmentioning

confidence: 95%

Regular hypnotic drug treatment in a sample of 32,679 Swedes: associations with somatic and mental health, inpatient psychiatric diagnoses and suicide, derived with automated record-linkage.

Allgulander

Näsman²

1991

Psychosomatic Medicine

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We studied Swedish survey responders who reported regular treatment with hypnotic drugs, to find associations to perceived health problems, inpatient psychiatric diagnoses, and subsequent suicide. Among 32,679 sampled Swedes, 26,952 (83%) participated, 500 of which (2%) reported regular hypnotic drug treatment. The rate of treatment was higher in women, and increased by age in both sexes. The major findings were high odds of concurrent psychoactive drug treatments, nervous symptoms and insomnia, as well as high rates of circulatory and musculoskeletal conditions in both sexes, with indicators of disability and sleep-disturbing symptoms. During a 15-year period, 35% of the men and 21% of the women who reported regular hypnotic drug treatment had also been admitted to inpatient psychiatric care. Substance abuse was diagnosed in 20% of the men and 4.3% of the women reporting hypnotic drug treatment. In multiple logistic regression models, the highest odds for regular hypnotic drug treatment were incurred by recent/current insomnia, nervous symptoms, and other psychoactive drug treatment. We conclude that therapy was principally given according to some current peer guidelines. Yet, further research is needed into the risk/benefit ratio of sustained hypnotic drug therapy in patients with qualifying somatic and psychiatric disorders to obtain a more uniformly based consensus.

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Section: Discussionmentioning

confidence: 95%

Regular hypnotic drug treatment in a sample of 32,679 Swedes: associations with somatic and mental health, inpatient psychiatric diagnoses and suicide, derived with automated record-linkage.

Allgulander

Näsman²

1991

Psychosomatic Medicine

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“…In one study, measures of heart rate variability were lower in PD patients during sleep (McCraty et al, 2001), which is consistent with less parasympathetic and more sympathetic activation, although heart rates did not differ. Heart rate and blood pressure are not elevated in PD during sleep (Abramson et al, 1989; Clark et al, 1990) unless patients have comorbid major depression (Abramson et al, 1989). As far as the authors know, skin conductance has never been reported for PD patients during sleep.…”

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confidence: 99%

Twenty-four hour skin conductance in panic disorder

Doberenz

Roth

Wollburg

et al. 2010

Journal of Psychiatric Research

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Skin conductance, physical activity, ambient temperature, and mood were recorded for 24 hours in 22 panic disorder (PD) patients and 29 healthy controls. During the day, subjects performed standardized relaxation tests (ARTs). We hypothesized that tonically elevated anticipatory anxiety in PD during waking and sleeping would appear as elevated skin conductance level (SCL) and greater skin conductance (SC) variability. Mean SCL was higher during both usual waking activities and sleeping in PD, but not during the ARTs. Group SC variability differences did not reach significance, perhaps because of variance unrelated to anxiety. Analyses indicated that in the PD group, antidepressant medication reduced mean SCL whereas state anxiety had the opposite effect during the day. Depressive symptoms reported during the day were related to elevated mean SCL on the night of the recording. The rate and extent of SCL deactivation over the night was equal in the two groups. However, PD patients had more frequent interruptions of deactivation that could have arisen from conditioned arousal in response to threat cues during sleep.

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Psychosocial Factors in Coronary Heart Disease

Gidron

2019

Behavioral Medicine

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Elevated sleep and waking heart rates in anxious depressions

Cited by 7 publications

References 10 publications

Regular hypnotic drug treatment in a sample of 32,679 Swedes: associations with somatic and mental health, inpatient psychiatric diagnoses and suicide, derived with automated record-linkage.

Regular hypnotic drug treatment in a sample of 32,679 Swedes: associations with somatic and mental health, inpatient psychiatric diagnoses and suicide, derived with automated record-linkage.

Twenty-four hour skin conductance in panic disorder

Psychosocial Factors in Coronary Heart Disease

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