Eleven years of experience with dialysis associated tuberculosis

Tuberculous lymphadenitis in patients undergoing continuous ambulatory peritoneal dialysis

“…A high prevalence of tuberculosis has been reported in dialysis patients, especially in areas where tuberculosis is endemic [2][3][4][5]. Extra-pulmonary tuberculosis is particularly common among dialysis patients and accounts for nearly 50% of cases [2][3][4][5]. Tuberculous (TB) lymphadenitis is a relatively common form of extra-pulmonary tuberculosis [6].…”

Interferon-γ Release Assays for Diagnosing Mycobacterium tuberculosis Infection in Renal Dialysis Patients

“…Renal failure patients are at 8 to 25 times higher risk for tuberculosis (TB) than the general population (3)(4)(5). TB disease in these patients can be difficult to diagnose, as it is frequently extrapulmonary and insidious in onset (6). Recommendations for screening dialysis patients for latent Mycobacterium tuberculosis infection (LTBI) exist to decrease transmission of TB in this setting of highly susceptible patients (7).…”

Guidelines for the prevention and management of Mycobacterium tuberculosis infection and disease in adult patients with chronic kidney disease

“…Symptoms usually developed within the first few weeks of treatment and included grand mal seizures (with no prior history), depressive psychosis, confusion, nightmares, hallucinations, peripheral neuropathy, twitching and dizziness. Encephalopathy was also reported in 3 of 48 dialysis patients with TB, 33 and neuropsychiatric side effects due to isoniazid have been reported elsewhere in the literature as case reports. 75e78 A quarter of those receiving dialysis also experienced significant gastrointestinal adverse effects (jaundice, nausea and vomiting).…”

“…33 42 43 Quantrill and colleagues 32 reported that 57% of cases of TB in patients on dialysis were peritoneal. Every effort should be made to obtain fluid or tissue for culture and sensitivity.…”