Elizabethkingia Meningoseptica sepsis Associated with COVID-19 Infection: An Emerging Nosocomial Pathogen

Rahi, Mandeep Singh; Amoah, Kwesi; Gunasekaran, Kulothungan; Kapil, R.; Kwon, Jeff

doi:10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2455

Cited by 3 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These similarities are indeed reflected in the case series presented here, emphasizing the risk associated with multimorbid patients admitted and treated for severe COVID-19 pneumonia. However, our case series highlights the incidence of multiple concomitant infections - including fungi - in these patients with EM bacteremia, as opposed to one instance of hospital-acquired pneumonia in the previously published case report [ 15 ].…”

Section: Discussionmentioning

confidence: 61%

Elizabethkingia meningoseptica Infection in COVID-19 Patients

Chaponda¹,

Shaukat²,

Dulli³

et al. 2022

Cureus

View full text Add to dashboard Cite

Bacterial and fungal coinfections including the emergence of antimicrobial resistance are well-recognized in the era of coronavirus disease 2019 (COVID-19) infections. We present three cases of Elizabethkingia meningoseptica (EM), superinfections in COVID-19 patients admitted between the period of April 2021 and May 2021. All cases were intubated; had central venous catheters, had received prior antibiotics and antivirals as well as dexamethasone as part of severe COVID-19 management. Only one patient received anakinra. EM isolates were resistant to most available antibiotics and patients infected with it had poor treatment outcomes.

show abstract

Section: Discussionmentioning

confidence: 61%

Elizabethkingia meningoseptica Infection in COVID-19 Patients

Chaponda¹,

Shaukat²,

Dulli³

et al. 2022

Cureus

View full text Add to dashboard Cite

show abstract

“…Elizabethkingia meningoseptica ( E. meningoseptica ), also known as Chryseobacterium meningosepticum and Flavobacterium meningosepticum , is a nonfermentative, nonmotile, oxidase- and catalase-positive, aerobic, gram-negative bacterium. 1 Although E. meningoseptica is ubiquitously distributed in water, soil and medical devices, E. meningoseptica infection in humans is relatively rare and was first reported in 1959. 2 E. meningoseptica is an opportunistic pathogen and primarily infects immunocompromised patients such as elders and neonates as well as those with sepsis, diabetes, malignant tumors, hypertension and critical conditions.…”

Section: Introductionmentioning

confidence: 99%

Emerging Prevalence and Clinical Features of Elizabethkingia meningoseptica Infection in Southwest China: A 9-Year Retrospective Study and Systematic Review

Ma¹,

Gong²,

Luo³

et al. 2023

IDR

View full text Add to dashboard Cite

Background Elizabethkingia meningoseptica infections have gradually emerged as life-threatening nosocomial infections worldwide, accompanied by increasing incidence, multidrug resistance and poor outcomes. However, the epidemiology and clinical features of E. meningoseptica infection are still limited in mainland China. Methods Patients with E. meningoseptica infections from 2011 to 2019 in southwestern China were retrospectively analyzed. The clinical features, infection patterns and outcomes were extracted from medical records and analyzed. A comprehensive systematic review was performed in accordance with PRISMA guidelines from conception to August 23, 2021. Results Ninety-two patients were ultimately included, with the prevalence rapidly rising from 0 in 2011 to 0.19 per 1000 inpatients in 2019. A total of 93.48% of E. meningoseptica isolates were multidrug resistant, including 100% resistance to carbapenem. Furthermore, 75% of E. meningoseptica infections were concomitant with other pathogens. The mortality of our cohort was 36.96%, with risk factors for mechanical ventilation (OR=9.51, P=0.004), male sex (OR=0.27, P=0.031) and more concomitant pathogens. After propensity score matching, central venous catheters, exposure to carbapenem and antifungal drugs, and underlying tumors were associated with E. meningoseptica infection. Sixteen articles were also summarized, with reported mortality rates ranging from 11.0% to 66.6%. Blood and respiratory tract were the common sources. Piperacillin/tazobactam, trimethoprim/sulfamethoxazole, fluoroquinolone and minocycline were the most sensitive antibiotics. Inappropriate antibiotic treatment was the most commonly reported risk factor for mortality. Conclusion Nosocomial infection with E. meningoseptica has become an emerging problem with high mortality in southwestern China. Inappropriate antibiotic treatment and central venous catheters are risk factors for infection and death and should receive adequate attention.

show abstract

Dexamethasone

2021

Reactions Weekly

View full text Add to dashboard Cite

Elizabethkingia Meningoseptica sepsis Associated with COVID-19 Infection: An Emerging Nosocomial Pathogen

Cited by 3 publications

References 0 publications

Elizabethkingia meningoseptica Infection in COVID-19 Patients

Elizabethkingia meningoseptica Infection in COVID-19 Patients

Emerging Prevalence and Clinical Features of Elizabethkingia meningoseptica Infection in Southwest China: A 9-Year Retrospective Study and Systematic Review

Dexamethasone

Contact Info

Product

Resources

About