Eltrombopag and its beneficial role in management of ulcerative Colitis associated with ITP as an upfront therapy case report

Abdelmahmuod, Elabbass; Ali, Elrazi; Ahmed, Mohanad; Yassin, Mohamed A

doi:10.1002/ccr3.3783

Cited by 3 publications

(1 citation statement)

References 7 publications

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“…This results in the phagocytosis of these platelets hence leading to a drop in circulating platelet count and, ultimately, thrombocytopenia [ 50 ]. Thrombopoietin receptor agonists and corticosteroids are most commonly used in the treatment of ITP [ 53 ].…”

Section: Resultsmentioning

confidence: 99%

Applications of Artificial Intelligence in Thrombocytopenia

et al. 2023

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Thrombocytopenia is a medical condition where blood platelet count drops very low. This drop in platelet count can be attributed to many causes including medication, sepsis, viral infections, and autoimmunity. Clinically, the presence of thrombocytopenia might be very dangerous and is associated with poor outcomes of patients due to excessive bleeding if not addressed quickly enough. Hence, early detection and evaluation of thrombocytopenia is essential for rapid and appropriate intervention for these patients. Since artificial intelligence is able to combine and evaluate many linear and nonlinear variables simultaneously, it has shown great potential in its application in the early diagnosis, assessing the prognosis and predicting the distribution of patients with thrombocytopenia. In this review, we conducted a search across four databases and identified a total of 13 original articles that looked at the use of many machine learning algorithms in the diagnosis, prognosis, and distribution of various types of thrombocytopenia. We summarized the methods and findings of each article in this review. The included studies showed that artificial intelligence can potentially enhance the clinical approaches used in the diagnosis, prognosis, and treatment of thrombocytopenia.

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Section: Resultsmentioning

confidence: 99%

Applications of Artificial Intelligence in Thrombocytopenia

et al. 2023

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A novel approach to immune thrombocytopenia intervention: modulating intestinal homeostasis

Sun,

Yan,

Fang

et al. 2024

BMC Immunol

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Immune thrombocytopenia (ITP) is a prevalent hemorrhage condition that causes notable immune-related abnormalities. Recently discovered data has shown that the intestinal flora plays a crucial role in maintaining a balanced immune system. Furthermore, an imbalance in gut flora has the potential to increase the possibility of developing ITP. Moreover, some studies reported a strong link between inflammatory bowel disease (IBD) and ITP. In this review, we described the significance of gut immunity in ITP. In addition, we explored the associations between gut flora and ITP as well as IBD and ITP. Finally, we examined the effectiveness of existing therapies that regulate gut homeostasis and their impact on the prognosis of patients with ITP.

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Management of Concurrent Immune Thrombocytopenia and Ulcerative Colitis: A Case Report and Literature Review

Hirai,

Mori,

Sakai

et al. 2024

Intern. Med.

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Eltrombopag and its beneficial role in management of ulcerative Colitis associated with ITP as an upfront therapy case report

Abstract: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Cited by 3 publications

References 7 publications

Applications of Artificial Intelligence in Thrombocytopenia

Applications of Artificial Intelligence in Thrombocytopenia

A novel approach to immune thrombocytopenia intervention: modulating intestinal homeostasis

Management of Concurrent Immune Thrombocytopenia and Ulcerative Colitis: A Case Report and Literature Review

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