Calcium carbonate scaling in industrial cooling circuits is a serious problem limiting the efficiency of heat exchanges. One preventive treatment consists in injecting an inhibitor polymeric additive in the circulating water. This work focuses on scaling experiments carried out in pilot plants, with and without additives, and simulated by using the CooliSS software (Cooling circuit Simulation Software) developed by EDF company. A local inhibition law of CaCO 3 crystal growth describing the adsorption of additives was found and implemented to calculate the global variation of calcium in the pilot plant. A small quantity of additive rapidly results in a decrease of the calcium deposit. The presence of suspended solids in water decreases the global inhibition by adsorption on other solids than calcite (illite and SiO 2 ). It was shown that the efficiency factors (inhibition ratios) depend on the nature of the surface (material) and on the presence of suspended particles in the cooling water.