EMAS position statement: Vitamin D and postmenopausal health

Pérez‐López, Faustino R.; Brincat, Marc; Erel, C. Tamer; Trémollières, Florence; Gambacciani, Marco; Lambrinoudaki, Ιrene; Moen, Mette Haase; Schenck‐Gustafsson, Karin; Vujović, Svetlana; Rozenberg, Serge; Rees, Margaret

doi:10.1016/j.maturitas.2011.11.002

Cited by 100 publications

(77 citation statements)

References 80 publications

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“…Limited sunlight exposure (25% of body surface/15 minutes a day) has been recommended to reach adequate 25(OH)D serum levels [29] [30]. In our study, as expected, patients exposed to sunlight showed higher 25(OH)D serum levels than those not ex- posed to solar radiation.…”

Section: Discussionsupporting

confidence: 85%

Hypovitaminosis D and Associated Risk Factors in Postmenopausal Women

Masoni¹,

Menoyo²,

Bocanera³

et al. 2014

Health

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Given the relevance of vitamin D in calcium metabolism homeostatic control, as well as its role as differentiation and cell proliferation modulator, it is important to study its circulating level in patients considered at risk, in order to develop prevention strategies. We studied 77 postmenopausal women with no history of osteoactive drug therapy, corticosteroid intake or diseases that could alter bone metabolism, attending the Menopause Center at the Hospital Provincial del Centenario, Rosario, Argentina. A medical history was taken, and a food consumption frequency questionnaire was applied in order to estimate daily calcium intake. To assess daily physical exercise, work and sports activities were investigated. Serum parathyroid hormone (PTH) and 25(OH)D were measured, and a hip DXA scan was performed in every patient. An inappropriate level of 25(OH)D was observed in 86.3% of patients. The 25(OH)D average value was found within the insufficiency range (<30 ng/ml) whereas PTH average concentration fell within the normal range, and bone mineral density average value was found within the osteopenic category. A statistically significant negative logarithmic association was observed between serum PTH level and vitamin D status (p = 0.01). Mean 25(OH)D concentration among patients who had reported fractures was significantly lower than the corresponding to women who had not suffered this type of event. Patients with vitamin D deficiency had significantly wider mean Cobb angle; higher sum of wedge angles of T4 -T12 vertebral bodies mean values, and higher uncompromised vertebrae wedge angle values than non-deficient women. This study shows high hypovitaminosis D occurrence among these postmenopausal women.

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Section: Discussionsupporting

confidence: 85%

Hypovitaminosis D and Associated Risk Factors in Postmenopausal Women

Masoni¹,

Menoyo²,

Bocanera³

et al. 2014

Health

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“…Consequently it may be advised to use lower calcidiol doses to take into account its highest efficacy, especially for long term maintenance supplementation. • Serum level: mainly advised to be above 30 ng/ml (75 nmol/l) [20,21,23,62]. IOM report [15] recommended a lower serum level 20 ng/ml (50 nmol/l) than other official organisations and raised concerns for serum levels above 50 ng/ml (125 nmol/l) because of the inverse "J" shape observed for mortality curves versus vitamin D serum levels [11,12].…”

Section: Discussion and Recommendationsmentioning

confidence: 99%

Vitamin D supplementation review and recommendations for women diagnosed with breast or ovary cancer in the context of bone health and cancer prognosis/risk

Martin-Herranz

Salinas-Hernández

2015

Critical Reviews in Oncology/Hematology

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“…De nombreux experts considèrent qu'une concentration inférieure à 20 ng/ml (soit 50 nmol/L) correspond à un déficit en vitamine D (c'est-à-dire ce qu'il faut éviter chez tout le monde) et qu'une concentration de 20 à moins de 30 ng/ml (soit 50-75 nmol/L) correspond à une insuffisance en vitamine D (c'est-à-dire ce qu'il faut éviter pour -au moins -un certain nombre de patients) (Adams et Hewison, 2010 ;Benhamou et al, 2011 ;Bischoff-Ferrari et al, 2006 ;Dawson-Hughes et al, 2005, 2010Holick et al, 2011 ;Perez-Lopez, 2012 ;Vieth, 2004). Cette valeur seuil de 30 ng/ml était basée initialement sur la relation entre la 25OHD et la PTH retrouvée dans des populations en bonne santé apparente (concentration de 25OHD au-dessous de laquelle la PTH peut s'élever).…”

Section: Définition De L'insuffisance En Vitamine Dunclassified

Actualités sur la vitamine D

Souberbielle

2014

OCL

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EMAS position statement: Vitamin D and postmenopausal health

Cited by 100 publications

References 80 publications

Hypovitaminosis D and Associated Risk Factors in Postmenopausal Women

Hypovitaminosis D and Associated Risk Factors in Postmenopausal Women

Vitamin D supplementation review and recommendations for women diagnosed with breast or ovary cancer in the context of bone health and cancer prognosis/risk

Actualités sur la vitamine D

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