The modern way of conducting combat operations has led to an expansion in the development of various combat systems. Experiences from modern military operations indicate that regardless of the place of combat operations, maneuvering ground or urban space, the systems for counter-attack ATGMs represent a very important weapon that contributes to the success of combat operations and is significantly represented in the arsenal of many armies. The paper presents the development of five generations of anti-armor missile systems, as important weapons whose main task is to destroy and neutralize tanks, combat armored vehicles, MRAP vehicles and non-combat vehicles, fortifications and bunkers at different firing ranges. Different tactical-technical features of the mentioned systems, development of several different types and generations of anti-aircraft missiles and the conditions in which they are used have led to the complexity of the problem of anti-aircraft missile systems research. An analysis of the development of anti-armor missile systems was carried out and a conclusion was drawn on the degree of efficiency of the mentioned systems in combat operations, with a proposal for the implementation of anti-armor missile systems of the third, fourth and fifth generation in infantry units. The paper also shows the requirements for the next generation of anti-armor systems.