2021
DOI: 10.21203/rs.3.rs-442878/v1
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

Embedding qualitative research in randomised controlled trials to improve recruitment: findings from two recruitment optimisation studies of orthopaedic surgical trials.

Abstract: Background: Recruitment of patients is one of the main challenges when designing and conducting randomised controlled trials (RCTs). Trials of rare injuries, or those that include surgical interventions pose added challenges due to the small number of potentially eligible patients and issues with patient preferences and surgeon equipoise. We explore key issues to consider when recruiting to orthopaedic surgical trials from the perspective of staff and patients with the aim of informing the development of strat… Show more

Help me understand this report
View published versions

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

1
4
0

Year Published

2022
2022
2022
2022

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(5 citation statements)
references
References 15 publications
1
4
0
Order By: Relevance
“…Key barriers underpinning decisions to decline participation in MedCan included gatekeeper influence, perceptions of risks outweighing benefits and aversion to randomised trials of unproven interventions. These reflect and confirm well-established barriers within the literature on RCT participation decision-making [8,13,49,58,66]. Specifically, when symptom burden was being sufficiently managed, several participants expressed a fear that trial participation would 'upset the apple cart'adversely interacting with their careful regime of medications.…”
Section: Discussionsupporting
confidence: 69%
See 4 more Smart Citations
“…Key barriers underpinning decisions to decline participation in MedCan included gatekeeper influence, perceptions of risks outweighing benefits and aversion to randomised trials of unproven interventions. These reflect and confirm well-established barriers within the literature on RCT participation decision-making [8,13,49,58,66]. Specifically, when symptom burden was being sufficiently managed, several participants expressed a fear that trial participation would 'upset the apple cart'adversely interacting with their careful regime of medications.…”
Section: Discussionsupporting
confidence: 69%
“…These finding suggest that barriers to RCT participation are both common and context-specific [49]; studies are always embedded within hospital, cultural and urban systems, with distinct policies, legal-political structures, urban density or sprawl and associated public transportation systems. Thus, while some have called for a 'methodological shift' toward employing the existing 'wealth of knowledge' on RCT recruitment challenges, rather than accumulating further evidence [13], this study shows the value of nesting qualitative sub-studies into RCTs: identifying and countering intervention-and settingspecific hurdles [14].…”
Section: Discussionmentioning
confidence: 82%
See 3 more Smart Citations