2007
DOI: 10.1007/s00270-007-9185-4
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Embolization of an Insulinoma of the Pancreas with Trisacryl Gelatin Microspheres as Definitive Treatment

Abstract: Insulinomas are rare, mostly benign neuroendocrine tumors, originating in 99% of cases from the pancreas, that synthesize and secrete insulin, causing symptomatic hypoglycemia. Today the treatment of choice is surgical removal. We present the case of an 84-year-old woman with a symptomatic insulinoma who refused surgery and was treated with arterial embolization using trisacryl gelatin microspheres as definitive treatment.

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Cited by 17 publications
(11 citation statements)
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“…Most patients with benign insulinomas can be cured with surgery, although other techniques for the management of insulinomas, including injection of octreotide, EUSguided alcohol ablation, radiofrequency ablation (RFA), or embolization of an insulinoma of the pancreas, have been described [55][56][57][58][59][60][61] .…”
Section: Medical Management Of Benign Insulinomasmentioning
confidence: 99%
See 1 more Smart Citation
“…Most patients with benign insulinomas can be cured with surgery, although other techniques for the management of insulinomas, including injection of octreotide, EUSguided alcohol ablation, radiofrequency ablation (RFA), or embolization of an insulinoma of the pancreas, have been described [55][56][57][58][59][60][61] .…”
Section: Medical Management Of Benign Insulinomasmentioning
confidence: 99%
“…Both patients were discharged without any complications and reported no further hypoglycemic episodes. Embolization of an insulinoma of the pancreas is another non-surgical alternative [55,67,68] . Because angiographically the insulinoma is demonstrated in the arterial phase as a hypervasculated mass, embolization could be performed using flow to direct particles exclusively into the tumor.…”
Section: Medical Management Of Benign Insulinomasmentioning
confidence: 99%
“…In patients at high surgical risk or in those refusing surgery, alternative local regional therapies can be offered. Several case reports and small series have been published reporting successful treatment of hypoglycaemia by transcutaneous or laparoscopically radiofrequency ablation, high-intensity focused ultrasound ablation (HIFU), ultrasound-assisted alcoholization or selective chemoembolization [25][26][27][28][29][30][31][32]. However, follow-up of patients treated with locoregional therapies is generally short, ranging from 5 weeks to 9 months; thus, additional data are needed to validate these techniques.…”
Section: Local-regional Ablative Therapymentioning
confidence: 99%
“…TAE is an effective procedure which is recommended for patients who are not eligible for or refuse surgery. Post-procedure complications of TAE including abdominal pain, mild pancreatitis and transitory mild diabetes were observed [15][16][17][18][19].…”
Section: Discussionmentioning
confidence: 99%