Embolization of arteriovenous malformations with peripheral aneurysms using ethylene vinyl alcohol copolymer

Terada, Tomoaki; Nakamura, Yuri; Nakai, Kenta; Tsuura, Mitsuharu; Nishiguchi, Takashi; Hayashi, Seiji; Kido, Takuhei; Taki, Waro; Iwata, Hiroo; Komai, Norihiko

doi:10.3171/jns.1991.75.4.0655

Cited by 74 publications

(31 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The application of EVOH in the endovascular treatment of intracranial AVMs was fi rst described by Taki et al [9] and Terada et al [10] in the early 1990s. Since that time, Onyx has been used for treatment of cerebral aneurysms and cerebral AVMs.…”

Section: Discussionmentioning

confidence: 99%

“…However, few studies have examined its use in other organs [8,9]. It was used for treatment of large intracranial aneurysms [5]; few cases of extracranial vascular lesions were treated with Onyx including treatment of type II endoleaks during EVAR (to embolize vessels that were feeding the aneurysm), for renal and celiac-mesenteric arterial aneurysms after the placing of protective balloons [7,8], pelvic arteriovenous fi stulas [3][4][5][6][7][8][9][10][11][12], and portal vascular anomalies [10].…”

Section: Discussionmentioning

confidence: 99%

“…There are only few reports concerning peripheral treatment with Onyx [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. We present our experience in the treatment of traumatic and non-traumatic peripheral vascular lesion with Onyx.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Embolization of traumatic and non-traumatic peripheral vascular lesions with Onyx

Regine¹,

Palmieri²,

Siero³

et al. 2015

Interventional Medicine and Applied Science

View full text Add to dashboard Cite

Abstract:Purpose: The aim of our study is to verify the feasibility and the effi cacy of Onyx as embolization agent in the treatment of traumatic and non-traumatic peripheral vascular lesions. Materials and Methods: In the period between September 2006 and March 2012, we treated with Onyx 26 patients (14 males/12 females; age range, 18-85 years old; mean age, 65 years old), 11 of which with traumatic peripheral vascular lesions and 15 with non-traumatic vascular lesions (9 neoplastic hemorrhagic lesions, 3 arteriovenous malformations (AVMs) and 3 aneurysms). Follow-up controls were performed with clinical examination and by multidetector computed tomography (MDCT) imaging 1, 6, and 12 months after the procedure. Results: All peripheral vascular lesions were embolized with Onyx; 3 patients with aneurysms were treated with Onyx associated with endovascular coils. Four elective and 22 emergency embolization procedures were performed. In all patients, we obtained cessation of bleeding and the complete and permanent embolization of all vascular lesions. Conclusions: Onyx is an eff ective and safe embolization agent for peripheral vascular lesions.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Embolization of traumatic and non-traumatic peripheral vascular lesions with Onyx

Regine¹,

Palmieri²,

Siero³

et al. 2015

Interventional Medicine and Applied Science

View full text Add to dashboard Cite

show abstract

“…Indications for embolization included acute hemorrhage (cases 1, 9, 11, 16 -18, and 21; n ϭ 14 sessions); recurrent episodic hemorrhage or oozing (cases 2,5,8,9,11,12,15,16, and 21; n ϭ 35 embolizations); discomfort or pain (cases 3,4,6,7,10,13,14,19,20, and 22; n ϭ 22 sessions), either in isolation or related to progressive tissue enlargement; impending necrosis secondary to ischemia or chronic infection; or functional impairment.…”

Section: Methodsmentioning

confidence: 99%

Safety and Clinical Efficacy of Onyx for Embolization of Extracranial Head and Neck Vascular Anomalies: Fig 1.

Thiex¹,

Wu²,

Mulliken³

et al. 2011

AJNR Am J Neuroradiol

View full text Add to dashboard Cite

show abstract

“…Generally liquid embolic agents such as N-butyl cyanoacrylate (n-BCA) and ethylene vinyl alcohol copolymer (EVOH) are used for the endovascular management of cerebral AVMs. The use of EVOH copolymers in AVMs was first reported by Terada et al (15). Later, Onyx was introduced and more widely used due to its slow polymerization and nonadhesive properties providing prolonged embolization times during the procedure (7,12).…”

Section: Squid Kullanımı Ile İlgili İlk Deneyim: Avm Av Fistül Ve Tümentioning

confidence: 99%

Preliminary experience with squid: a new liquid embolizing agent for avm, av fistulas and tumors

Akmangit¹,

Dağlıoğlu²,

Kaya³

et al. 2014

Turkish Neurosurgery

View full text Add to dashboard Cite

The aim of the present study was to analyze our experience with a new liquid embolic agent, Squid, for the treatment of cerebral vascular lesions. MATERIAL and METHODS:We present 28 patients who were treated with two formulations of Squid (Squid 18 and Squid 12). The lesions included 16 arteriovenous malformation (AVM)s (Spetzler-Martin grade 2 in 8, 3 in 6 and 4 in 2), 9 arteriovenous (AV) fistulas, 2 tumors (glomus tumor and angiofibroma) and 1 AICA aneurysm. Of the 9 patients presenting with hemorrhage, 6 were AVM, 2 were AVF and 1 was aneurysm. RESULTS:The total obliteration rate of the AVMs was 37.5%. Fistulas were closed completely after combined treatment with surgery in 6 out of 9 patients, and one was sent to radiotherapy. There was no mortality. Two reported hemorrhages and thromboembolic complications resulted in permanent deficits in 3 patients. Pathologic examination revealed mild inflammatory reaction with infiltration of polymorphonuclear cells in 5 patients in whom surgery was performed immediately after embolization. Technical problems such as rupture, inability to remove or premature occlusion of the microcatheter related to the embolic agent were not recorded. CONCLUSION:Squid is a safe and effective embolic agent for treatment of cerebral AVMs, AV fistulas, tumors and aneurysms with satisfactory obliteration rate.KEywORDS: Squid, Cerebral arteriovenous malformation, Intracranial AVM, Intracranial AV fistula, Tumor, Embolization ÖZ AMAÇ: Çalışmada amaç yeni bir sıvı embolik ajan olan Squid'in serebral vasküler lezyonların tedavisindeki deneyimimizi analiz etmektir. yÖNTEM ve GEREÇLER: Çalışmada Squid 18 ve Squid 12 olmak üzere iki ayrı Squid formülasyonu ile tedavi edilen 28 hasta sunulmaktadır. Lezyonlar arasında 16 arteriyovenöz malformasyon (AVM) (Spetzler-Martin Evre 2 olan 8, Evre 3 olan 6 ve Evre 4 olan 2 olgu), 9 arteriyovenöz (AV) fistül, 2 tümör (glomus tümörü ve anjiyofibrom) ve 1 AICA anevrizması yer almaktadır. Kanama ile prezente olan 9 hastanın 6'sı AVM, 2'si AV fistül ve 1'si anevrizmadır.BULGULAR: AVM lezyonlarında toplam kapanma oranı %37,5 olarak hesaplandı. Fistüllerin 9'undan 6'sı cerrahi ile kombine tedavi sonrası kapatıldı, 1 olgu radyoterapiye gönderildi. Mortalite izlenmedi. Bildirilen iki kanama ve tromboembolik komplikasyonlar 3 hastada kalıcı defisite neden oldu. Embolizasyon sonrası hemen cerrahi yapılan 5 hastadaki patolojik incelemeler, polimorfonükleer hücreleri içeren hafif enflamatuvar reaksiyonu gösterdi. Rüptür, mikrokateterin çıkarılamaması veya erken oklüzyonu gibi teknik problemler izlenmedi. SONUÇ:Squid serebral AVM, AV fistül, tümör ve anevrizmaların tedavisinde güvenli ve efektif bir embolik ajan olup tatminkar obliterasyon oranlarına sahiptir.

show abstract

Embolization of arteriovenous malformations with peripheral aneurysms using ethylene vinyl alcohol copolymer

Cited by 74 publications

References 5 publications

Embolization of traumatic and non-traumatic peripheral vascular lesions with Onyx

Embolization of traumatic and non-traumatic peripheral vascular lesions with Onyx

Safety and Clinical Efficacy of Onyx for Embolization of Extracranial Head and Neck Vascular Anomalies: Fig 1.

Preliminary experience with squid: a new liquid embolizing agent for avm, av fistulas and tumors

Contact Info

Product

Resources

About