Percutaneous coronary angioplasty can be associated with a number of complications. The most dangerous and fatal for patients is coronary artery perforation. In most cases, this damage is caused by direct damage to the vessel shear with the instruments used, such as balloons, stents, or guidewires. Treatment can be difficult, especially when standard methods are inadequate. This review presents the most important techniques used in the treatment of coronary artery perforations.