Embryo cryopreservation: Evidence for practice

Granne, Ingrid; Child, Tim; Hartshorne, Geraldine M.

doi:10.1080/14647270802242205

Cited by 10 publications

(6 citation statements)

References 105 publications

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“…Eighteen studies were accepted into this review, totalling 2,616 women and 395 blastocyst implantations. The total number of births in this study was unclear, and there were variations in the trials reviewed, so generalizing these results to the entire population seeking assisted reproductive technology (ART) is difficult (17). Nonetheless, a meta-analysis similarly demonstrated that live-birth rates were higher after blastocyst transfer (OR 1.39; 95% CI, 1.10-1.76, P¼ .005) when compared with cleavage-stage transfer (8).…”

mentioning

confidence: 62%

Outcomes of singleton births after blastocyst versus nonblastocyst transfer in assisted reproductive technology

Fernando

Halliday

Breheny

et al. 2012

Fertility and Sterility

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mentioning

confidence: 62%

Outcomes of singleton births after blastocyst versus nonblastocyst transfer in assisted reproductive technology

Fernando

Halliday

Breheny

et al. 2012

Fertility and Sterility

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“…The oocytes are then fertilized on the day of recovery, and fertilization is evident 24 h later. There is debate as to the optimal time to cryopreserve embryos 64 but it is most commonly carried out on day two or three. The majority of good‐quality embryos will survive cryopreservation and thawing but, in the context of fertility preservation, there will be a tendency to preserve as many embryos as possible, which will then impact on survival and implantation rates.…”

Section: Embryo and Oocyte Cryopreservationmentioning

confidence: 99%

Fertility preservation in girls and young women

Anderson

Wallace

2011

Clinical Endocrinology

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There is increasing interest and experience in the options available to preserve fertility in those about to undergo potentially gonadotoxic chemotherapy or radiation therapy, usually related to treatment for cancer. Recent years have seen the development of methods for prepubertal girls, female adolescents and adult women, although these remain less established than sperm cryopreservation for men. At present, the options for prepubertal boys remain experimental. Embryo cryopreservation following ovarian stimulation and IVF is a routine procedure technically and its success in the management of infertility is established. However, there are no data on uptake or success rates in the context of fertility preservation in women with cancer. Oocyte cryopreservation is technically challenging and requires ovarian stimulation, thus potentially resulting in a delay in cancer treatment. Oocyte vitrification offers increased success rates in comparison with slow freezing; however, this approach is also limited by the number of oocytes that can be obtained. The third possibility, ovarian tissue cryopreservation, can be performed without significant delay and is the only option for prepubertal girls. Worldwide, a small number of children have been born following reimplantation of frozen/ thawed ovarian tissue. It is clear that fertility preservation is important for some girls and young women facing treatments that will compromise their fertility, but the availability of all approaches varies widely. Effective approaches for prepubertal boys are also required.

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“…The need for a direct comparison of the two treatments by a prospective RCT has been indicated by a Cochrane review (8), the British Fertility Society (9), and subsequent to the initiation of this study, a recent systematic review (10).…”

mentioning

confidence: 99%