Embryo transfer technique as a cause of ectopic pregnancy in in vitro fertilization

Nazari, Ahmad; Askari, Hasan; Check, Jerome H.; O’Shaughnessy, Althea

doi:10.1016/s0015-0282(16)56297-9

Cited by 109 publications

(4 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Depth of transfer may also have an effect; a randomized prospective study of deep versus mid-fundal transfer reported an EP rate of 1.5 versus 0.4 % [57]. Day of embryo transfer has inconsistently been associated with risk of EP in prior studies.…”

Section: Reviewmentioning

confidence: 99%

Incidence, diagnosis and management of tubal and nontubal ectopic pregnancies: a review

Panelli

Phillips

Brady

2015

Fertil Res and Pract

207

251

View full text Add to dashboard Cite

BackgroundEctopic pregnancy is a potentially life-threatening condition occurring in 1-2 % of all pregnancies. The most common ectopic implantation site is the fallopian tube, though 10 % of ectopic pregnancies implant in the cervix, ovary, myometrium, interstitial portion of the fallopian tube, abdominal cavity or within a cesarean section scar.FindingsDiagnosis involves a combination of clinical symptoms, serology, and ultrasound. Medical management is a safe and effective option in most clinically stable patients. Patients who have failed medical management, are ineligible, or present with ruptured ectopic pregnancy or heterotopic pregnancy are most often managed with excision by laparoscopy or, less commonly, laparotomy. Management of nontubal ectopic pregnancies may involve medical or surgical treatment, or a combination, as dictated by ectopic pregnancy location and the patient's clinical stability. Following tubal ectopic pregnancy, the rate of subsequent intrauterine pregnancy is high and independent of treatment modality.ConclusionThis review describes the incidence, risk factors, diagnosis, and management of tubal and non-tubal ectopic and heterotopic pregnancies, and reviews the existing data regarding recurrence and future fertility.

show abstract

Section: Reviewmentioning

confidence: 99%

Incidence, diagnosis and management of tubal and nontubal ectopic pregnancies: a review

Panelli

Phillips

Brady

2015

Fertil Res and Pract

207

251

View full text Add to dashboard Cite

show abstract

“…( 8 ) conducted a randomized controlled trial that found a lower rate of ectopic pregnancy among patients who underwent embryo transfer using a midfundal (>15 mm from fundus) compared with a deep fundal technique. It has been hypothesized that the distance of the catheter tip to the fundus may increase the risk of ectopic pregnancy by bringing the embryo in closer proximity to the tubal ostia ( 8 , 9 ). Similarly, a higher velocity during embryo transfer may also help propel the embryo closer or into the tubal ostia.…”

Section: Discussionmentioning

confidence: 99%

The use of an embryo transfer simulator to compare transfer techniques and pregnancy outcomes among physicians

McQueen,

Borazjani,

Yeh

et al. 2024

F&S Reports

View full text Add to dashboard Cite

“…Assisted reproductive techniques are a known risk factor for ectopic pregnancies [21]; the risk varies according to the technique employed with intrafallopian transfers conferring the highest risk [22, 23], a technique which has fallen out of practice. Regarding intrauterine transfers, midfundal techniques reduced the risk of ectopic pregnancy by 75% when compared to the deep fundal technique [22].…”

Section: Discussionmentioning

confidence: 99%

“…Regarding intrauterine transfers, midfundal techniques reduced the risk of ectopic pregnancy by 75% when compared to the deep fundal technique [22]. A large multicenter trial showed that the risk with ART is significantly higher if there is preexisting tubal factor infertility [24].…”

Section: Discussionmentioning

confidence: 99%

Unilateral Atraumatic Expulsion of an Ectopic Pregnancy in a Case of Bilateral Ectopic Pregnancy

Sampson

Mogekwu

Ahmed

et al. 2017

Case Reports in Obstetrics and Gynecology

View full text Add to dashboard Cite

Ectopic pregnancy occurs in 1-2% of pregnancies. The fallopian tube is the most common site; however, bilateral tubal ectopic pregnancy is an extremely rare phenomenon, seen in approximately 1/200,000 pregnancies. It is usually the result of assisted reproductive techniques (ART). Ultrasound (USS) and serial beta-hCG levels have shown poor efficacy for accurate diagnosis. Laparoscopy is the diagnostic gold standard. The majority of cases are managed surgically with bilateral salpingectomy. A 26-year-old female presented to our early pregnancy unit with pain and vaginal bleeding at 5-week gestation after IVF. USS was inconclusive and her b-hCG levels rose with worsening pain; therefore, a decision was made for diagnostic laparoscopy. Although there was a clear right sided ectopic pregnancy, the left tube was swollen and therefore a methylene blue dye test was carried out to confirm blockage. Atraumatic milking, to expose the dye, expelled necrotic tissue which histology confirmed to be a second ectopic pregnancy. She made a good recovery with falling beta-hCG levels and left tubal preservation. As the use of ART increases, bilateral ectopic pregnancies will become more common. Novel and established techniques should be used to help confirm the diagnosis and assist in tubal preservation.

show abstract

Embryo transfer technique as a cause of ectopic pregnancy in in vitro fertilization

Cited by 109 publications

References 4 publications

Incidence, diagnosis and management of tubal and nontubal ectopic pregnancies: a review

Incidence, diagnosis and management of tubal and nontubal ectopic pregnancies: a review

The use of an embryo transfer simulator to compare transfer techniques and pregnancy outcomes among physicians

Unilateral Atraumatic Expulsion of an Ectopic Pregnancy in a Case of Bilateral Ectopic Pregnancy

Contact Info

Product

Resources

About