Embryogenesis of the Skin

Lee, Lara Wine; Holbrook, Karen A.

doi:10.1002/9781119142812.ch1

Cited by 2 publications

(2 citation statements)

References 118 publications

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“…During fetal development, skin water content progressively decreases from a composition of 92% water at 13 weeks to 90% at 20 weeks and 83% water at term 11 . Stratum corneum hydration decreases rapidly in the first day after birth and then increases over the first 3 weeks of life, according to a study of term infants 12 . Increased edema, which is typically noted in low-gestational-age infants, causes less adhesion between the dermis and epidermis, making the skin susceptible to deformation by external pressure from medical devices 11 …”

Section: Skin Developmentmentioning

confidence: 99%

Neonatal Skin Structure: Pressure Injury Staging Challenges

Nie

Johnson

Reed

2022

Adv Skin Wound Care

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To review neonatal pressure injuries (PIs), including clinical features and challenges in evaluation and staging related to the unique anatomic features of preterm neonatal skin as well as the common sites and mechanisms of injury.TARGET AUDIENCE: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES: After participating in this educational activity, the participant will: 1. Recognize the causes of PIs in preterm neonates. 2. Choose the outcomes of PIs in preterm neonates. 3. Distinguish the common characteristics of preterm neonates' skin. 4. Summarize the challenges clinicians face when classifying the PIs of preterm neonates.

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Section: Skin Developmentmentioning

confidence: 99%

Neonatal Skin Structure: Pressure Injury Staging Challenges

Nie

Johnson

Reed

2022

Adv Skin Wound Care

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“…Після втрати лануго в області скальпа з'являється волосся двох типів: термінальне (постійне) і пушкове. Паралельно з розвитком волосся відбувається утворення сальних залоз, секрет яких утворює на поверхні шкіри плода сироподібну змазку (vernix caseosa), яка захищає шкіру від мацерації внаслідок тривалого контакту з навколоплідними водами [5,7,8].…”

Section: анатомія і розвиток волосяних фолікулів і сальних залозunclassified

Androgen-associated and androgen-independent causes of alopecia and acne in women. Literature review

Сидорова

Тутченко

Бурка

et al. 2020

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This article refers to the issues of alopecia and acne pathogenesis: anatomy of hair and sebaceous glands, biological factors affecting the stages of hair development and function of sebaceous glands. Alopecia is divided into two large groups: scaring and non-scaring alopecia, the later is represented by alopecia areata, telogen effluvium, and female pattern hair loss/androgenetic alopecia (FPHL/AGA). Before starting the search for systemic causes it is necessary to predetermine the type of alopecia on the basis of medical history and external manifestations. FPHL /AGA as a most common form of alopecia can often coexist with another common pathology – telogen effluvium, this fact determines therapeutic approaches and their results.Main pathogenetic mechanisms, approaches to differential diagnostics and treatment of the main specified types of non-scarring alopecia are reviewed. FPHL/AGA is a main type of alopecia which is often referred to gynecologists/endocrinologists. It is now regarded a multifactorial pathology with the involvement of a genetic component, androgen receptor gene expression, dihydrotestosterone synthesis and local low grade inflammation specifics. FPHL/AGA can be with and without hyperandrogenism, in both cases it can be accompanied by an increased risk of metabolic syndrome. In case of FPHL/AGA with hyperandrogenism the success of treatment depends on the consistent coordinated work of gynecologist/endocrinologist and dermatologist/trichologist, which allows combining systemic and local therapy in a timely manner.Also contemporary views on the acne pathogenesis are reviewed. Given the complex nature of acne its therapy is also complex and stepwise. According to current clinical guidelines and recent studies of the microbial component of acne pathogenesis the following conclusions are formulated. Patients with acne require assessment of androgen status, determination of the hyperandrogenism source, including evaluation of tissue androgens; phenotype of the syndrome and cardio-metabolic risks should be determined in patients with polycystic ovary syndrome; it is advisable to determine antimicrobial susceptibility of pathogens isolated from the inflamed pilosebaceous unit if acne form requires the local or systemic antibacterial therapy.

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Embryogenesis of the Skin

Cited by 2 publications

References 118 publications

Neonatal Skin Structure: Pressure Injury Staging Challenges

Neonatal Skin Structure: Pressure Injury Staging Challenges

Androgen-associated and androgen-independent causes of alopecia and acne in women. Literature review

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