Embryonal rhabdomyosarcoma of the rectum: report of a case and possible treatment option

Marnewick, Jacques; Hulme-Moir, Michael

doi:10.1111/j.1463-1318.2009.01877.x

Cited by 2 publications

(1 citation statement)

References 3 publications

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“…Other rare malignant spindle cell tumours described at this site include embryonal rhabdomyosarcoma, angiosarcoma, dermatofibrosarcoma protruberans, Kaposi's sarcoma, de‐differentiated liposarcoma, low‐grade fibromyxoid sarcoma, sarcomatoid/spindle cell carcinoma and sarcomatoid renal cell carcinoma …”

Section: Malignant Melanoma: Primary and Metastaticmentioning

confidence: 99%

Spindle cell proliferations of the sigmoid colon, rectum and anus: a review with emphasis on perineurioma

Grech

Schofield

2020

Histopathology

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A wide range of spindle cell proliferations are found uncommonly in the sigmoid colon, rectum and anus. They usually present as polyps, and include reactive lesions and benign and malignant neoplasms which may be primary or metastatic. They are less frequently described in the literature compared to those in the upper gastrointestinal tract, and may be underdiagnosed. The widespread use of sigmoidoscopy in symptomatic patients and bowel cancer screening programmes means that histopathologists must be aware of, and adopt a logical approach to, diagnosing spindle cell proliferations in biopsy and polypectomy specimens. This is particularly relevant given the strong association of some mesenchymal polyps with hereditary cancer syndromes. This review article will focus on perineurioma and the recent debate in relation to its overlap with fibroblastic polyp. The clinical, endoscopic, histological and immunohistochemical features of spindle cell proliferations which should be considered in the differential diagnosis of perineurioma will be discussed. There is also a brief reference to malignant spindle cell tumours of diagnostic importance.

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Section: Malignant Melanoma: Primary and Metastaticmentioning

confidence: 99%

Spindle cell proliferations of the sigmoid colon, rectum and anus: a review with emphasis on perineurioma

Grech

Schofield

2020

Histopathology

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Rectum Sarcoma: Challenging Diagnostic and Therapeutic Modalities

Mastoraki

Psarras

Mastoraki

et al. 2013

J Gastrointest Canc

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The size and depth of invasion are the most important prognostic factors. Since they grow within the intestinal wall, the symptoms are usually few or late, leading to delays in diagnosis. Most common signs are rectal bleeding, abdominal or anal pain, diarrhea, tenesmus and weight loss. The diagnostic and staging protocol of stromal tumors of the rectum includes mainly endoscopic surveillance, computed tomography, and magnetic resonance imaging. Therefore, rectum sarcoma (RS) consists one of the most biologically virulent cancers and is difficult to cure by conventional procedures. The treatment is primarily surgical, where possible, and should guarantee complete clearance of the tumor, which often requires an aggressive approach. Unfortunately, the minority of patients is eligible to undergo surgical intervention. In addition, surgical removal of RS does not necessarily indicate a patient's long-term recovery. Alternative therapies, such as radio- and chemotherapy, proved insufficient. Elucidation of its molecular basis may prove useful in developing and identifying prognostic biomarkers.

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Embryonal rhabdomyosarcoma of the rectum: report of a case and possible treatment option

Abstract: Figure 1 Macroscopic view of the resected specimen, showing complex cystic arrangement. Inset: microscopic view showing highly cellular appearance of tumour.e170 Ó

Cited by 2 publications

References 3 publications

Spindle cell proliferations of the sigmoid colon, rectum and anus: a review with emphasis on perineurioma

Spindle cell proliferations of the sigmoid colon, rectum and anus: a review with emphasis on perineurioma

Rectum Sarcoma: Challenging Diagnostic and Therapeutic Modalities

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