Embryonic Fundulus heteroclitus responses to sediment extracts from differentially contaminated sites in the Elizabeth River, VA

Volkoff, Savannah J.; Osterberg, Joshua S.; Jayasundara, Nishad; Cooper, Ellen M.; Hsu‐Kim, Heileen; Rogers, Laura; Gehrke, Gretchen E.; Jayaraman, Saro; Giulio, Richard T. Di

doi:10.1007/s10646-019-02116-z

Cited by 8 publications

(4 citation statements)

References 35 publications

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“…This has also been demonstrated in field-caught adults, wherein adult killifish from JC had the most striking decrease in aerobic scope compared to KC . One possible explanation for the marked persistent fitness costs in JC killifish compared to other ER fish is a possible unknown contaminant present at the JC site driving the changes in metabolic response, though it is important to note that PAHs, PCBs, and extractable trace metals measured at JC in 2014 were moderate compared to the other sites in the ER …”

Section: Discussionmentioning

confidence: 60%

“…19 One possible explanation for the marked persistent fitness costs in JC killifish compared to other ER fish is a possible unknown contaminant present at the JC site driving the changes in metabolic response, though it is important to note that PAHs, PCBs, and extractable trace metals measured at JC in 2014 were moderate compared to the other sites in the ER. 37 Though the present study and others have established a strong link between PAH adaptation and bioenergetic changes, 19,20 little is understood about how killifish respond following the removal of the high selection pressure, a phenomenon known as "relaxed selection". 38 Remediation efforts at MP and AW have been successful in significantly reducing PAH contamination at these sites over the last 10−15 years.…”

Section: ■ Discussionmentioning

confidence: 73%

“…Remediation efforts at MP and AW have been successful in significantly reducing PAH contamination at these sites over the last 10–15 years. At MP, remediation reduced the total selected PAHs from 124,381 ng/g dry sediment in 2007 to 2729.7 ng/g in 2014. At AW, remediation reduced the total selected PAHs from 122,665 ng/g dry sediment in 2008 to between 38 and 720 ng/g in 2018.…”

Section: Discussionmentioning

confidence: 99%

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Bioenergetic Effects of Polycyclic Aromatic Hydrocarbon Resistance Manifest Later in Life in Offspring of Fundulus heteroclitus from the Elizabeth River

Jasperse,

Di Giulio,

Jayasundara

2023

Environ. Sci. Technol.

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Shifts in key physiological processes can confer resistance to chemical pollutants. However, these adaptations may come with certain trade-offs, such as altered energy metabolic processes, as evident in Atlantic killifish (Fundulus heteroclitus) in Virginia’s Elizabeth River (ER) that have evolved resistance to polycyclic aromatic hydrocarbons (PAHs). We seek to understand the bioenergetic costs of PAH resistance among subpopulations of Atlantic killifish with differing contamination levels in order to examine how these changes manifest across multiple life stages and how these costs might be exacerbated by additional stressors. Bioenergetics data revealed differences in metabolic rates between offspring of PAH-resistant fish and reference fish were absent or minimal in both the embryo and larval stages but pronounced at the juvenile life stage, suggesting that bioenergetic changes in pollution-adapted killifish manifest later in life. We also provide evidence that killifish from remediated sites are more sensitive to PAH exposure than killifish from nonremediated sites, suggesting loss of PAH tolerance following relaxed selection. Collectively, our data suggest that the fitness consequences associated with evolved resistance to anthropogenic stressors may manifest differently over time and depend on the magnitude of the selection pressure. This information can be valuable in effective risk and remediation assessments as well as in broadening our understanding of species responses to environmental change.

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Section: Discussionmentioning

confidence: 60%

Section: ■ Discussionmentioning

confidence: 73%

Section: Discussionmentioning

confidence: 99%

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Bioenergetic Effects of Polycyclic Aromatic Hydrocarbon Resistance Manifest Later in Life in Offspring of Fundulus heteroclitus from the Elizabeth River

Jasperse,

Di Giulio,

Jayasundara

2023

Environ. Sci. Technol.

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“…PAHs Exposure has been well established to disrupt or impair the natural function of endocrine systems in teleost (Dey et al, 2019;. Similarly, PAHs were discovered to activate Cytochrome P450-1A, a gene up-regulator of toxins and by induction of the aryl hydrocarbon receptor and were established to be responsible for teratogenic effects and embryonic cardiac deformities on exposed killifish embryos (Volkoff et al, 2019). In addition, Grung et al, 2016 documented PAHs exposure to Eurasian minnow (Phoxinus phoxinus) where activation of cytochrome 450 A1 was observed, DNA adduct and PAHs metabolites formation seen.…”

Section: Pahs In Aquatic Organismsmentioning

confidence: 99%

Ecotoxicity and Associated Threat of Polycyclic Aromatic Hydrocarbons (PAHs) to Biodiversity: A Review

Zungum¹,

Imam²

2021

Preprint

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There is a sustained rise in incidence of cancer and toxicity related to chemicals exerting enormous burden to public health and biodiversity. Polycyclic Aromatic Hydrocarbons (PAHs) are mong such contaminants, precisely the sixteen-priority characterized by United States Environmental Protection Agency (USEPA). Therefore, this review is aimed at further elaboration about the 16 USEPA characterized PAHs and threat portend to public health and biodiversity. PAHs are a class of very stable organic pollutants produced most commonly, by incomplete combustion of fossil fuel and are formed when complex organic substances are exposed to heat. PAHs in great amount due to build up over time by bioaccumulation can be perilous: to human beings of all age and levels, aquatic organisms, amphibians and reptiles. The soil like the aquatic environment contains substantial quantity of PAHs since, atmospheric PAHs sediments on the soil due to dry and wet deposition, terrestrial organism are impacted if the soil is saturated with PAHs. Therefore, PAHs are a great source of trepidation for food safety, public health and biodiversity sustenance. Hence, tackling the spade of the menacing ubiquity of PAHs becomes necessary from its sources by encouragement of alternatives to petroleum fuels for machines and vehicles.

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Identifying bioaugmentation candidates for bioremediation of polycyclic aromatic hydrocarbons in contaminated estuarine sediment of the Elizabeth River, VA, USA

Volkoff

Rodriguez

Singleton

et al. 2022

Appl Microbiol Biotechnol

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Embryonic Fundulus heteroclitus responses to sediment extracts from differentially contaminated sites in the Elizabeth River, VA

Cited by 8 publications

References 35 publications

Bioenergetic Effects of Polycyclic Aromatic Hydrocarbon Resistance Manifest Later in Life in Offspring of Fundulus heteroclitus from the Elizabeth River

Bioenergetic Effects of Polycyclic Aromatic Hydrocarbon Resistance Manifest Later in Life in Offspring of Fundulus heteroclitus from the Elizabeth River

Ecotoxicity and Associated Threat of Polycyclic Aromatic Hydrocarbons (PAHs) to Biodiversity: A Review

Identifying bioaugmentation candidates for bioremediation of polycyclic aromatic hydrocarbons in contaminated estuarine sediment of the Elizabeth River, VA, USA

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