Emergence, Natural History, and Variation of Canine, Mink, and Feline Parvoviruses

Parrish, Colin R.

doi:10.1016/s0065-3527(08)60867-2

Cited by 140 publications

(90 citation statements)

References 119 publications

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“…These all correspond to speci¢c di¡erences between the pathogens (e.g. pH dependence, which may be su¤cient to explain the speci¢city for canid versus feline cells) (Parrish 1990). …”

Section: Emerging Infectious Pathogens Of Wildlife a Dobson And J Fmentioning

confidence: 99%

Emerging infectious pathogens of wildlife

Dobson

Foufopoulos

2001

Phil. Trans. R. Soc. Lond. B

532

408

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The ¢rst part of this paper surveys emerging pathogens of wildlife recorded on the ProMED Web site for a 2-year period between 1998 and 2000. The majority of pathogens recorded as causing disease outbreaks in wildlife were viral in origin. Anthropogenic activities caused the outbreaks in a signi¢cant majority of cases. The second part of the paper develops some matrix models for quantifying the basic reproductive number, R 0 , for a variety of potential types of emergent pathogen that cause outbreaks in wildlife. These analyses emphasize the sensitivity of R 0 to heterogeneities created by either the spatial structure of the host population, or the ability of the pathogens to utilize multiple host species. At each stage we illustrate how the approach provides insight into the initial dynamics of emergent pathogens such as canine parvovirus, Lyme disease, and West Nile virus in the United States.

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“…These all correspond to speci¢c di¡erences between the pathogens (e.g. pH dependence, which may be su¤cient to explain the speci¢city for canid versus feline cells) (Parrish 1990). …”

Section: Emerging Infectious Pathogens Of Wildlife a Dobson And J Fmentioning

confidence: 99%

Emerging infectious pathogens of wildlife

Dobson

Foufopoulos

2001

Phil. Trans. R. Soc. Lond. B

532

408

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“…Diseases include enteritis, in the case of canine parvovirus (CPV) [1,2], and childhood fifth disease, caused by the human pathogen B19 [3,4]. Parvoviruses infect only actively proliferating (S phase) cells [5].…”

Section: Introductionmentioning

confidence: 99%

The structure of a neutralized virus: canine parvovirus complexed with neutralizing antibody fragment

et al. 1994

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Background-Members of the Parvovirus genus cause a variety of diseases in mammals, including humans. One of the major defences against viral infection is the presence of neutralizing antibodies that prevent virus particles from infecting target cells. The mechanism of neutralization is not well understood. We therefore studied the structure of canine parvovirus (CPV) complexed with the Fab fragment of a neutralizing antibody, A3B10, using image reconstruction of electron micrographs of vitrified samples, together with the already known structure of CPV from X-ray crystallographic data.

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“…Outbreaks of canine parvovirus type-2 (CPV-2) infection are characterized by high morbidity and mortality, and have spread rapidly worldwide since 1978 [11,23]. The appearance of new subtype of this virus generally present less severe disease in dogs that have a better survival rate [24,26].…”

mentioning

confidence: 99%

Clinical Effects of the Recombinant Feline Interferon-.OMEGA. on Experimental Parvovirus Infection in Beagle Dogs.

1998

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ABSTRACT. The clinical effects of recombinant feline interferon-ω (rFeIFN-ω), produced in silkworm by recombinant baculovirus, were examined in 3-4 month-old beagle dogs given an experimental canine parvovirus type-2 (CPV-2) infection. Clinical symptoms, such as pyrexia, vomiting, anorexia and diarrhea, were observed on day 4 after oral inoculation of 10 7 TCID 50 of CPV-2 (cc 238 strain) in almost all the inoculated dogs. From day 4, rFeIFN-ω (1 mega units/kg/day) or physiological saline was administered intravenously to infected dogs for 3 consecutive days. Seven out of 17 dogs treated with physiological saline showed hemorrhagic diarrhea and continuously expressed severe clinical enteritis; one dog died with a large amount of hemorrhagic rice-water stool on day 6 after viral exposure. In contrast, 4 out of 12 dogs treated with rFeIFN-ω showed severe clinical enteritis associated with intermittent diarrhea. Scoring of fecal condition revealed that treatment with rFeIFN-ω significantly shifted the enteritis from a severe to mild form. Furthermore, rFeIFN-ω administered in the morning decreased the number of dogs expressing clinical enteritis in the evening suggesting a rapid effect. Vomiting and anorexia were also improved by treatment with rFeIFN-ω. These results suggest that rFeIFN-ω can reduce severe enteritis caused by CPV-2 infection in dogs. -KEY WORDS: beagle dog, canine parvovirus, enteritis, experimental infection, recombinant feline interferon-ω.J.

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Emergence, Natural History, and Variation of Canine, Mink, and Feline Parvoviruses

Cited by 140 publications

References 119 publications

Emerging infectious pathogens of wildlife

Emerging infectious pathogens of wildlife

The structure of a neutralized virus: canine parvovirus complexed with neutralizing antibody fragment

Clinical Effects of the Recombinant Feline Interferon-.OMEGA. on Experimental Parvovirus Infection in Beagle Dogs.

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