Emergence of a deviating genotype VI pigeon paramyxovirus type-1 isolated from India

Ganar, Ketan; Das, Moushumee; Raut, Ashwin Ashok; Mishra, Anamika; Kumar, Sachin

doi:10.1007/s00705-017-3340-2

Cited by 11 publications

(4 citation statements)

References 45 publications

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“…This system was widely adopted, and its use resulted in the identification of three more genotypes (XVI, XVII, and XVIII) (Courtney et al, 2013; Snoeck et al, 2013b). In addition, multiple sub-genotypes have been proposed within many of the existing genotypes (Ahmadi et al, 2016; Byarugaba et al, 2014; Chumbe et al, 2017; Das and Kumar, 2017; Dimitrov et al, 2016b; Esmaelizad et al, 2017; Ganar et al, 2017; He et al, 2018; Miller et al, 2015; Molini et al, 2017; Nath and Kumar, 2017; Ramey et al, 2017; Ramey et al, 2013; Sabouri et al, 2017; Sabra et al, 2017; Servan de Almeida et al, 2013; Snoeck et al, 2013a; Susta et al, 2014; Xue et al, 2017a; Xue et al, 2017b).…”

Section: Introductionmentioning

confidence: 99%

“…In other instances, new genotypes were created without applying all of the proposed criteria, or the classification was completed using a limited sequence dataset (often using partial F gene sequences) rather than using a curated dataset of all available complete NDV F gene sequences. For these reasons, there are inconsistencies in the naming and classification of some newly proposed genotypes and some sub-genotypes bear identical names while describing different and unrelated viruses (Ahmadi et al, 2016; Barman et al, 2017; Das and Kumar, 2017; Esmaelizad et al, 2017; Ganar et al, 2017; Gowthaman et al, 2018; Nath and Kumar, 2017; Servan de Almeida et al, 2013; Snoeck et al, 2013a; Xue et al, 2017a). Furthermore, with the increased surveillance efforts and the improvement of sequencing technologies, the amount of available sequences has vastly increased, adding to the already complex challenge of studying the molecular evolution of NDV and the relationships among its isolates.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Updated unified phylogenetic classification system and revised nomenclature for Newcastle disease virus

Dimitrov

Abolnik

Afonso

et al. 2019

Infection, Genetics and Evolution

304

397

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Several Avian paramyxoviruses 1 (synonymous with Newcastle disease virus or NDV, used hereafter) classification systems have been proposed for strain identification and differentiation. These systems pioneered classification efforts; however, they were based on different approaches and lacked objective criteria for the differentiation of isolates. These differences have created discrepancies among systems, rendering discussions and comparisons across studies difficult. Although a system that used objective classification criteria was proposed by Diel and co-workers in 2012, the ample worldwide circulation and constant evolution of NDV, and utilization of only some of the criteria, led to identical naming and/or incorrect assigning of new sub/genotypes. To address these issues, an international consortium of experts was convened to undertake in-depth analyses of NDV genetic diversity. This consortium generated curated, up-to-date, complete fusion gene class I and class II datasets of all known NDV for public use, performed comprehensive phylogenetic neighbor-Joining, maximum-likelihood, Bayesian and nucleotide distance analyses, and compared these inference methods. An updated NDV classification and nomenclature system that incorporates phylogenetic topology, genetic distances, branch support, and epidemiological independence was developed. This new consensus system maintains two NDV classes and existing genotypes, identifies three new class II genotypes, and reduces the number of sub-genotypes. In order to track the ancestry of viruses, a dichotomous naming system for designating sub-genotypes was introduced. In addition, a pilot dataset and sub-trees rooting guidelines for rapid preliminary genotype identification of new isolates are provided. Guidelines for sequence dataset curation and phylogenetic inference, and a detailed comparison between the updated and previous systems are included. To increase the speed of phylogenetic inference and ensure consistency between laboratories, detailed guidelines for the use of a supercomputer are also provided. The proposed unified classification system will facilitate future studies of NDV evolution and epidemiology, and comparison of results obtained across the world.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Updated unified phylogenetic classification system and revised nomenclature for Newcastle disease virus

Dimitrov

Abolnik

Afonso

et al. 2019

Infection, Genetics and Evolution

304

397

View full text Add to dashboard Cite

show abstract

“…This mAb panel is neither widely available nor commonly used, and not all viruses from genotype VI (and genotype XXI that was created from viruses formerly belonging to genotype VI) have been shown to be PPMV-1. Of note, while the term PPMV-1 has initially been used to designate only the viruses of sub-genotype VI.1.1, it has also been often used for all viruses from genotype VI without evidence that they are indeed PPMV-1 [ 20 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

A Pigeon-Derived Sub-Genotype XXI.1.2 Newcastle Disease Virus from Bangladesh Induces High Mortality in Chickens

Nooruzzaman

Barman

Mumu

et al. 2021

Viruses

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Newcastle disease virus (NDV) is a significant pathogen of poultry; however, variants also affect other species, including pigeons. While NDV is endemic in Bangladesh, and poultry isolates have been recently characterized, information about viruses infecting pigeons is limited. Worldwide, pigeon-derived isolates are commonly of low to moderate virulence for chickens. Here, we studied a pigeon-derived NDV isolated in Bangladesh in 2010. To molecularly characterize the isolate, we sequenced its complete fusion gene and performed a comprehensive phylogenetic analysis. We further studied the biological properties of the virus by estimating mean death time (MDT) and by experimentally infecting 5-week-old naïve Sonali chickens. The studied virus clustered in sub-genotype XXI.1.2 with NDV from pigeons from Pakistan isolated during 2014–2018. Deduced amino acid sequence analysis showed a polybasic fusion protein cleavage site motif, typical for virulent NDV. The performed in vivo pathogenicity testing showed a MDT of 40.8 h, and along with previously established intracerebral pathogenicity index of 1.51, these indicated a velogenic pathotype for chickens, which is not typical for pigeon-derived viruses. The experimental infection of chickens resulted in marked neurological signs and high mortality starting at 7 days post infection (dpi). Mild congestion in the thymus and necrosis in the spleen were observed at an advanced stage of infection. Microscopically, lymphoid depletion in the thymus, spleen, and bursa of Fabricius were found at 5 dpi, which progressed to severe in the following days. Mild to moderate proliferation of glial cells was noticed in the brain starting at 2 dpi, which gradually progressed with time, leading to focal nodular aggregation. This study reports the velogenic nature for domestic chickens of a pigeon-derived NDV isolate of sub-genotype XXI.1.2. Our findings show that not all pigeon-derived viruses are of low virulence for chickens and highlight the importance of biologically evaluating the pathogenicity of NDV isolated from pigeons.

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“…The real-time reverse transcriptase-polymerase chain reaction (rRT-PCR) is a test that satisfies the requirements for high sensitivity and specificity, coupled with a short turnaround time [4,6,7,11,17].…”

mentioning

confidence: 99%

Detection of Newcastle Disease Virus (NDV) in Laughing Doves and the Risk of Spread to Backyard Poultry

et al. 2020

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Newcastle disease (ND) is a highly infectious viral disease of birds caused by the Newcastle disease virus (NDV) and doves have been incriminated in previous outbreaks of the disease that have discouraged backyard poultry productions. This survey was done to detect and characterize the NDV from 184 swabs from the cloacae and pharynxes of 67 trapped laughing doves and 25 backyard poultry birds. The study utilized haemagglutination assay (HA) followed by haemagglutination inhibition (HI) tests on HA positive samples to screen field samples. Conventional reverse transcriptase polymerase chain reaction (RT-PCR) was conducted on the HI positives to characterize the NDV. This study revealed that of 134 dove samples screened, 88 (65.7 %) were HA positive. Of these HA positives subjected to HI testing, 37 (42.1 %) were HI positive. Interestingly, 21 (56.8 %) of the HI positives were also RT-PCR positive: 8 lentogenic, 12 velogenic, while one had both lentogenic and velogenic NDV. Comparatively, of the 50 chicken samples screened, 23 (46 %) were HA positive; and of these, HA positives subjected to HI testing, 16 (69.6 %) were HI positive. Only 4 (25 %) of the HI positives were RTPCR positive: 3 lentogenic and a velogenic NDV. From this study it was concluded that laughing doves were demonstrated to be infected with either lentogenic or velogenic NDV or both. The use of red blood adsorption-de-adsorption concentration of NDV enhanced the RT-PCR detection using the fusion gene primers NDV-F 4829 and NDV-R 5031. The detection of not only lentogenic but velogenic NDV in laughing doves poses a great risk to backyard poultry production.

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Emergence of a deviating genotype VI pigeon paramyxovirus type-1 isolated from India

Cited by 11 publications

References 45 publications

Updated unified phylogenetic classification system and revised nomenclature for Newcastle disease virus

Updated unified phylogenetic classification system and revised nomenclature for Newcastle disease virus

A Pigeon-Derived Sub-Genotype XXI.1.2 Newcastle Disease Virus from Bangladesh Induces High Mortality in Chickens

Detection of Newcastle Disease Virus (NDV) in Laughing Doves and the Risk of Spread to Backyard Poultry

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