Abstract:Flagellar and ciliary oscillations result from a combination of stereotypical axonemal geometry, collective mechanics of motors, microtubules (MTs), elastic linkers and biochemical regulation. However, the minimal essential components and constraints resulting in flagellar oscillations remain unclear. Here, we demonstrate that periodic, low-frequency waves of flagella-like oscillations in vitro emerge from a ATP-driven collective molecular motor transport of MTs clamped at one end. The spontaneous oscillations… Show more
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