Emergence of fluoroquinolone-resistant strains of Salmonella enterica in Surabaya, Indonesia

Yanagi, Daisuke; Vries, Garry Cores de; Rahardjo, Dadik; Alimsardjono, Lindawati; Wasito, Eddy Bagus; De, Ismoedijanto; Kinoshita, Shouhiro; Hayashi, Yoshitake; Hotta, Hak; Osawa, Ro; Kawabata, Masato; Shirakawa, Toshiro

doi:10.1016/j.diagmicrobio.2009.04.006

Cited by 21 publications

(12 citation statements)

References 21 publications

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“…S. Typhi isolates were obtained in routine health examinations within 3 days after the workers entered Taiwan, and some isolates were recovered from typhoid carriers due to epidemiological investigation of typhoid cases. MDR S. Typhi and ciprofloxacin-resistant S. Typhi strains were noted in Surabaya, Indonesia, in 2008 (38). However, 53 of the 55 Indonesian isolates characterized in this study were pan-susceptible ( Table 2), and the majority were very clonal ( Fig.…”

Section: Discussionmentioning

confidence: 83%

Antimicrobial Resistance in Salmonella enterica Serovar Typhi Isolates from Bangladesh, Indonesia, Taiwan, and Vietnam

Chiou

Lauderdale

Phung

et al. 2014

Antimicrob Agents Chemother

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We characterized Salmonella enterica serovar Typhi isolates from Bangladesh, Indonesia, Taiwan, and Vietnam to investigate their genetic relatedness and antimicrobial resistance. The isolates from Bangladesh and Vietnam were genetically closely related but were distant from those from Indonesia and Taiwan. All but a few isolates from Indonesia and Taiwan were susceptible to all antimicrobials tested. The majority of isolates from Bangladesh and Vietnam were multidrug resistant (MDR) and belonged to the widespread haplotype H58 clone. IncHI1 plasmids were detected in all MDR S. Typhi isolates from Vietnam but in only 15% of MDR isolates from Bangladesh. Resistance genes in the majority of MDR S. Typhi isolates from Bangladesh should reside in the chromosome. Among the isolates from Bangladesh, 82% and 40% were resistant to various concentrations of nalidixic acid and ciprofloxacin, respectively. Several resistance mechanisms, including alterations in gyrase A, the presence of QnrS, and enhanced efflux pumps, were involved in the reduced susceptibility and resistance to fluoroquinolones. Intensive surveillance is necessary to monitor the spread of chromosome-mediated MDR and fluoroquinolone-resistant S. Typhi emerging in Bangladesh.

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Section: Discussionmentioning

confidence: 83%

Antimicrobial Resistance in Salmonella enterica Serovar Typhi Isolates from Bangladesh, Indonesia, Taiwan, and Vietnam

Chiou

Lauderdale

Phung

et al. 2014

Antimicrob Agents Chemother

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“…(9, 11) On the other hand, the number of serovar Typhi isolates with reduced susceptibility to fluoroquinolones was high, a problem also noted in other Asian countries. (23–27)…”

Section: Discussionmentioning

confidence: 99%

Incidence of Typhoid Bacteremia in Infants and Young Children in Southern Coastal Pakistan

Owais

Sultana

Zaman

et al. 2010

Pediatric Infectious Disease Journal

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“…Asian countries where MDRTF have been reported include China (1985), Pakistan (1987), India (1988), Malaysia (1991), Singapore (1994), Bangladesh (1994), Vietnam (1995), Japan (1999), Thailand (2001), Korea (2003), Nepal (2005) and Indonesia (2009); other countries include Kuwait (1996) and Jordan (2008) [1,36,38,[45][46][47][48][49][50][51][52][53]. A recent multi-centric study conducted across five Asian countries (China, India, Indonesia, Pakistan, and Vietnam) that are endemic for typhoid reported the prevalence of multidrugresistant S. Typhi strains ranging from 7% to 65% [54].…”

Section: Global Prevalencementioning

confidence: 99%

Multidrug-resistant typhoid fever: a review

Zaki

Karande

2011

J Infect Dev Ctries

128

116

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Introduction: Multidrug-resistant typhoid fever (MDRTF) is defined as typhoid fever caused by Salmonella enterica serovar Typhi strains (S. Typhi), which are resistant to the first-line recommended drugs for treatment such as chloramphenicol, ampicillin and trimethoprimsulfamethoxazole. Since the mid-1980s, MDRTF has caused outbreaks in several countries in the developing world, resulting in increased morbidity and mortality, especially in affected children below five years of age and those who are malnourished. Methodology: Two methods were used to gather the information presented in this article. First PubMed was searched for English language references to published relevant articles. Secondly, chapters on typhoid fever in standard textbooks of paediatric infectious diseases and preventive and social medicine were reviewed. Results: Although there are no pathognomonic clinical features of MDRTF at the onset of the illness, high fever ( > 104°F), toxaemia, abdominal distension, abdominal tenderness, hepatomegaly and splenomegaly are often reported. The gold standard for the diagnosis of MDRTF is bacterial isolation of the organism in blood cultures. Ciprofloxacin and ceftriaxone are the drugs most commonly used for treatment of MDRTF and produce good clinical results. Conclusion: MDRTF remains a major public health problem, particularly in developing countries. Mass immunization in endemic areas with either the oral live attenuated Typhi 21a or the injectable unconjugated Vi typhoid vaccine, rational use of antibiotics, improvement in public sanitation facilities, availability of clean drinking water, promotion of safe food handling practices and public health education are vital in the prevention of MDRTF.

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Emergence of fluoroquinolone-resistant strains of Salmonella enterica in Surabaya, Indonesia

Cited by 21 publications

References 21 publications

Antimicrobial Resistance in Salmonella enterica Serovar Typhi Isolates from Bangladesh, Indonesia, Taiwan, and Vietnam

Antimicrobial Resistance in Salmonella enterica Serovar Typhi Isolates from Bangladesh, Indonesia, Taiwan, and Vietnam

Incidence of Typhoid Bacteremia in Infants and Young Children in Southern Coastal Pakistan

Multidrug-resistant typhoid fever: a review

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