Emergence of Marburg Virus Disease in West Africa amid COVID-19 and Ebola: Efforts, Challenges, and Recommendations to Prevent the Next Public Health Crisis

Lawrence, Jannel A; Ul, Rasool Muhammad Haseeb; Parikh, Charmy; Selia, Chowdhury; Alexandra, Sueldo; Sarosh, Sarwar; Arpit, Mago; Kumar, Thada Pawan; Mona, Skeikh

doi:10.23937/2474-3658/1510259

Cited by 10 publications

(17 citation statements)

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“…1 Avoid contact with bodily fluids [29] Avoid contact with blood, urine, feces, saliva, sweat, vomit, breast milk, amniotic fluid, semen, and vaginal fluids of infected individuals 2 Transfer suspected cases to healthcare system [30] Any suspected case should instantly be transferred to a healthcare system for treatment and isolation instead of managing at home 3 Proceed with caution during aerosol-generating procedures [31] When doing procedures that generate aerosols, proceed with utmost caution 4 Use protective gear when handling wildlife [30] Use gloves and other suitable protective gear while handling wildlife 5 Use infection prevention and control measures [32] Health and care providers should use IPC measures, such as conventional and transmission-based precautions when caring for patients with confirmed or suspected MVD 6 Safer sexual activities for male survivors [28] Male MVD survivors must engage in safer sexual activities and maintain better personal hygiene until their semen tests Marburg virus-free twice 7 Safely dispose of infected dead bodies [31] MVD infected dead bodies should be safely disposed of…”

Section: Measure Descriptionmentioning

confidence: 99%

Marburg virus disease is a looming threat in the Republic of Guinea

Javairia,

Babar,

Abid

et al. 2024

International Journal of Surgery: Global Health

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Section: Measure Descriptionmentioning

confidence: 99%

Marburg virus disease is a looming threat in the Republic of Guinea

Javairia,

Babar,

Abid

et al. 2024

International Journal of Surgery: Global Health

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“…Hemorrhagic signs like bleeding gums, petechiae, purpura, subconjunctival injection, and gastrointestinal bleeding include hematochezia and melena that appear on progression. Disturbed blood components reveal during laboratory investigation [9][10][11] . These findings represented leukopenia, thrombocytopenia, and lymphopenia.…”

Section: Mode Of Transmission and Clinical Manifestations Of Marburg ...mentioning

confidence: 99%

“…Person-to-person transmission can happen in settings like homes or hospitals when infection control measures are less effective. Human contracts MARV through sexual interaction and direct contact with body fluids 8,9 . The virus penetrates the mucosa with an incubation period of 3–21 days, which differs according to the dose and route of infection 1,10 .…”

Section: Introductionmentioning

confidence: 99%

First Marburg virus outbreak in Equatorial Guinea; what should we do to prevent future occurrence?

Oduoye,

Nazir,

Nazir

et al. 2023

International Journal of Surgery: Global Health

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“…This includes guidelines for handling and burying bodies safely, often with the involvement of trained personnel [12, 13]. Moreover, there is a need for continued investment in research and strengthening one health approach to develop new vaccines and treatments for infectious diseases [2, 14].…”

Section: Recommendations For Future Outbreaks Of Mvdmentioning

confidence: 99%

Marburg virus outbreak in Tanzania: A threat to global health security

Edward,

Scott,

John

et al. 2023

Public Health Challenges

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The current Marburg virus (MARV) outbreak in Tanzania served as a stark reminder of the ongoing threat posed by emerging infectious diseases and the urgent need for global health security. The Tanzanian Ministry of Health (MoH) officially declared the outbreak on March 21, 2023. Eight cases in all, five of which included fatalities, have been reported in the country at present. The virus is a member of the Filoviridae family closely related to the widely known Ebola virus. Similar to other filoviruses, MARV causes acute and lethal hemorrhagic fever in both human and nonhuman primates with high case fatality rates ranging from 24% to 90%. The outbreak has highlighted the need for improved disease surveillance and response systems, as well as increased funding for research into emerging infectious diseases. The Tanzanian MoH has deployed a response team to investigate and monitor the transmission in the Kagera Region. The team works closely in collaboration with other organizations, such as the World Health Organization and the Africa Centre for Disease Control and Prevention, to ensure the effective control of the situation. Although there is no vaccine or treatment approved for Marburg virus disease (MVD), supportive management improves survival. Existing infection prevention and control protocols for Ebola and other viral hemorrhagic fevers such as isolation and use of appropriate personal protective equipment can be used to prevent transmission of MVD. The global community must work together to strengthen health systems, enhance research efforts, and build resilient and responsive health systems to prevent future outbreaks of this kind. In this article, we have analyzed the MVD outbreak in Tanzania, specifically in the Bukoba district of the Kagera Region, and provided recommendations for the management of the current outbreak and future outbreaks.

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Emergence of Marburg Virus Disease in West Africa amid COVID-19 and Ebola: Efforts, Challenges, and Recommendations to Prevent the Next Public Health Crisis

Cited by 10 publications

References 0 publications

Marburg virus disease is a looming threat in the Republic of Guinea

Marburg virus disease is a looming threat in the Republic of Guinea

First Marburg virus outbreak in Equatorial Guinea; what should we do to prevent future occurrence?

Marburg virus outbreak in Tanzania: A threat to global health security

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