Emergence of Zika virus infection in China

Zhou, Chunkui; Liu, Jianwei; Qi, Rui; Fang, Li-Zhu; Qin, Xiang-Rong; Han, Hui-Ju; Mo, Rong-Can; Yu, Honggang; Jiao, Yongjun; Lin, Jian; Yu, Xue‐Jie

doi:10.1371/journal.pntd.0008300

Cited by 17 publications

(13 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A 2017 study of healthy adults (n = 801) in Vietnam estimated 1.1% seroprevalence using a ZIKV neutralization assay ( 39 ). An additional study in Guangxi Province, China, in March 2019 found 6% of 273 participants bound to ZIKV NS1 using IgG ELISA testing and neutralized ZIKV in cell cultures ( 40 ). Those past studies, especially those relying on tests of whole Zika virions and full-length antigens, had poor specificity, mainly because of antibodies induced by DENV infections cross-reacting with ZIKV antigens.…”

Section: Discussionmentioning

confidence: 99%

Novel Assay to Measure Seroprevalence of Zika Virus in the Philippines

Adams¹,

Jadi²,

Segovia-Chumbez³

et al. 2021

Emerg. Infect. Dis.

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Novel Assay to Measure Seroprevalence of Zika Virus in the Philippines

Adams¹,

Jadi²,

Segovia-Chumbez³

et al. 2021

Emerg. Infect. Dis.

View full text Add to dashboard Cite

“…A globally approved dengue vaccine is still under development, and there is no specific treatment for dengue fever [28]. In addition, studies have shown that residents in China and Southeast Asia also face potential threats from the Zika virus [29].…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition and Antifungal, Anti-Inflammatory, Antiviral, and Larvicidal Activities of the Essential Oils of Zanthoxylum acanthopodium DC. from China and Myanmar

Yang

Song

et al. 2022

Molecules

View full text Add to dashboard Cite

Zanthoxylum acanthopodium DC. is a widely used traditional medicinal plant to treat fever, flu, stomachache, traumatic injury, and mosquito bite in tropical and subtropical Asia. This study aimed to investigate the antifungal, anti-inflammatory, antiviral, and larvicidal activities of its fruit essential oil. The essential oil sample from China (EOZC) was mainly composed of limonene (29.78%) and β-myrcene (26.65%), while the sample from Myanmar (EOZM) was dominated by Terpinen-4-ol (43.35%). Both essential oils showed antifungal activity, with 90% minimum inhibitory concentration (MIC90) values ranging from 26.3 to 499 μg/mL. By obviously inhibiting nitric oxide (NO) in RAW 264.7 cells, EOZC (IC50, 16 μg/mL) showed comparable anti-inflammatory activity to the positive control L-NMMA (IC50, 12.2 μg/mL). EOZM showed significant antiviral activity against the dengue virus with an IC50 value of 13 μg/mL. Additionally, both EOZC and EOZM demonstrated dose-dependent larvicidal activity against Aedes albopictus, with LC50 and LC90 values ranging from 45.8 to 144.0 μg/mL. Our results contribute a theoretical foundation for the further application of Zanthoxylum acanthopodium DC. as an antifungal and anti-inflammatory ingredient in the pharmaceutical industry and further indicate that it has the potential to be developed as a new source of natural and eco-friendly medicine for the prevention and treatment of dengue virus.

show abstract

“…Liaoning province is located in northeast of China, where neither Zika nor Dengue virus [ 8 , 9 ] are endemic. Although Liaoning province had a low prevalence of JE [ 10 ], there was an outbreak of 69 cases with a 30.4% fatality rate in the summer of 2018, which was very similar to the prevalence of JEV infection in the north of Ningxia in 2018 [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

The underlying mechanism of Guillain-Barré syndrome in a young patient suffered from Japanese encephalitis virus infection: a case report

Liu

Wang

Yang

et al. 2022

Virol J

View full text Add to dashboard Cite

Background The presentation of Guillain–Barré syndrome (GBS) caused by Japanese encephalitis virus (JEV) is uncommon, although clusters of GBS cases were observed in China in 2018. The underlying mechanism is unclear, particularly in individuals vaccinated against Japanese encephalitis in childhood. Case presentation We report a patient with acute flaccid paralysis involving four extremities and respiratory muscles, while magnetic resonance imaging of the brain and spine were standard. Electrophysiological examination displayed slowed motor nerve conduction speed and reduced evoked velocity amplitude. GBS was finally considered which was related to JEV infection verified by positive anti-JEV immunoglobulin M antibody and positive immunoglobulin G antibody in the serum. Unfortunately, the patient refused intravenous immunoglobulin and declined the use of mechanical ventilation again. He voluntarily withdrew from the hospital and died on the 36th day after the onset of illness. We also performed a review of previously reported related cases and discussed the underlying mechanism. Conclusion JEV infection-associated GBS is unusual. We should pay attention to the atypical manifestations of JEV infection and explore possible pathogenesis in particular individuals.

show abstract

Emergence of Zika virus infection in China

Cited by 17 publications

References 25 publications

Novel Assay to Measure Seroprevalence of Zika Virus in the Philippines

Novel Assay to Measure Seroprevalence of Zika Virus in the Philippines

Chemical Composition and Antifungal, Anti-Inflammatory, Antiviral, and Larvicidal Activities of the Essential Oils of Zanthoxylum acanthopodium DC. from China and Myanmar

The underlying mechanism of Guillain-Barré syndrome in a young patient suffered from Japanese encephalitis virus infection: a case report

Contact Info

Product

Resources

About