Emergency Care of Crisis Conditions in Myasthenia Gravis

Abstract

The article presents an analysis of current data on emergency management of crises in patients with myasthenia gravis, which is supplemented by our own observations of 892 patients with myasthenia gravis. A follow-up study was conducted, which helped us to assess the frequency, nature and course of crises in patients with myasthenia gravis, taking into account the form of the disease, sex and age of patients. It was found that crises were observed in 154 (17.4%) patients, these conditions were significantly more often registered at the age of 20 to 40 and in the first three years of the disease. Myasthenic crises 149 (96.9%) prevailed among the crises and were registered mainly in patients with generalized and pharyngeal-facial myasthenia. Based on long-term follow-up of patients and assessment of the results of emergency management of myasthenic crises we have presented an optimal scheme for prescription of anticholinesterase medicines as a part of combined therapy of crises of varying severity.