2008
DOI: 10.1016/j.ijcard.2007.02.005
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Emergency coronary artery bypass grafting in patients with acute myocardial infarction treated with glycoprotein IIb/IIIa receptor inhibitors

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Cited by 10 publications
(9 citation statements)
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“…The increased use of coronary stents and glycoprotein IIb/IIIa inhibitors has markedly reduced the incidence of emergent and urgent coronary artery bypass graft surgery for unsuccessful percutaneous coronary intervention [13]. Moreover, a number of studies demonstrated that the use of tirofiban after unsuccessful percutaneous coronary angioplasty does not increase the incidence of bleeding after urgent coronary artery bypass operations [14][15]. However, no previous studies of the impact of tirofiban on myocardial performance after heart surgery are currently available.…”
Section: Discussionmentioning
confidence: 99%
“…The increased use of coronary stents and glycoprotein IIb/IIIa inhibitors has markedly reduced the incidence of emergent and urgent coronary artery bypass graft surgery for unsuccessful percutaneous coronary intervention [13]. Moreover, a number of studies demonstrated that the use of tirofiban after unsuccessful percutaneous coronary angioplasty does not increase the incidence of bleeding after urgent coronary artery bypass operations [14][15]. However, no previous studies of the impact of tirofiban on myocardial performance after heart surgery are currently available.…”
Section: Discussionmentioning
confidence: 99%
“…Severe thrombocytopenia (platelet count <20,000/μL) occurred in approximately 0.7% of patients receiving abciximab for the first time, more often than with either eptifibatide or tirofiban (0.2%). 375 A pooled analysis of 8 placebo-controlled studies concluded that abciximab, but not eptifibatide or tirofiban, increased the incidence of thrombocytopenia in patients also treated with heparin. 375 …”
Section: Pharmacology and Pharmacokineticsmentioning
confidence: 99%
“…375 A pooled analysis of 8 placebo-controlled studies concluded that abciximab, but not eptifibatide or tirofiban, increased the incidence of thrombocytopenia in patients also treated with heparin. 375 …”
Section: Pharmacology and Pharmacokineticsmentioning
confidence: 99%
“…331 Although the data are inconsistent, increased perioperative bleeding in patients undergoing cardiac and vascular surgery after receiving GPIIb/IIIa antagonists has been noted. 337 In general, the cardiac surgical and interventional radiology literature recommend that elective surgery be delayed 24 to 48 hours after abciximab and 4 to 8 hours after eptifibatide or tirofiban. For semiurgent surgery, if possible, delay until the antiplatelet effects have significantly dissipated (approximately 12-24 hours for abciximab, and 4-6 hours for peptidomimetic agents like eptifibatide or tirofiban) is advocated.…”
Section: Pharmacology and Pharmacokineticsmentioning
confidence: 99%
“…335 Surgery performed within 12 hours of abciximab administration will most likely necessitate a platelet transfusion as has been shown in patients having coronary artery bypass grafting. 337 Although rare, abciximab, eptifibatide, and tirofiban can produce thrombocytopenia immediately after drug administration in a small proportion of patients. Reactions usually occur within hours but may occasionally be delayed.…”
Section: Pharmacology and Pharmacokineticsmentioning
confidence: 99%