Emergency Department Care for Patients with Hemophilia and Von Willebrand Disease

Singleton, Tammuella; Kruse‐Jarres, Rebecca; Leissinger, Cindy

doi:10.1016/j.jemermed.2007.12.024

Cited by 40 publications

(43 citation statements)

References 11 publications

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“…Nevertheless, desmopressin has been recommended in patients treated with platelet inhibitors, suffering from intracerebral bleeding [438,453] and in trauma patients with von Willebrand disease [466]. Interestingly, desmopressin prevents the development of hypothermia-induced impairment of primary haemostasis [467] and significantly increases platelet aggregation during hypothermia and acidosis [468].…”

Section: Resultsmentioning

confidence: 99%

Management of bleeding and coagulopathy following major trauma: an updated European guideline

Bouillon²,

et al. 2013

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IntroductionEvidence-based recommendations are needed to guide the acute management of the bleeding trauma patient. When these recommendations are implemented patient outcomes may be improved.MethodsThe multidisciplinary Task Force for Advanced Bleeding Care in Trauma was formed in 2005 with the aim of developing a guideline for the management of bleeding following severe injury. This document represents an updated version of the guideline published by the group in 2007 and updated in 2010. Recommendations were formulated using a nominal group process, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) hierarchy of evidence and based on a systematic review of published literature.ResultsKey changes encompassed in this version of the guideline include new recommendations on the appropriate use of vasopressors and inotropic agents, and reflect an awareness of the growing number of patients in the population at large treated with antiplatelet agents and/or oral anticoagulants. The current guideline also includes recommendations and a discussion of thromboprophylactic strategies for all patients following traumatic injury. The most significant addition is a new section that discusses the need for every institution to develop, implement and adhere to an evidence-based clinical protocol to manage traumatically injured patients. The remaining recommendations have been re-evaluated and graded based on literature published since the last edition of the guideline. Consideration was also given to changes in clinical practice that have taken place during this time period as a result of both new evidence and changes in the general availability of relevant agents and technologies.ConclusionsA comprehensive, multidisciplinary approach to trauma care and mechanisms with which to ensure that established protocols are consistently implemented will ensure a uniform and high standard of care across Europe and beyond.Please see related letter by Morel et alhttp://ccforum.com/content/17/4/442

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Section: Resultsmentioning

confidence: 99%

Management of bleeding and coagulopathy following major trauma: an updated European guideline

Bouillon²,

et al. 2013

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“…Tedavideki gecikmeler ekstremite kaybına ve hatta ölümlere yol açabileceğinden major kanamayla acil servise gelen hastalarda eksik pıhtılaşma faktörle-rinin hızlıca yerine konması hatta tanısal laboratuar testlerinin faktör seviyesi yükseldikten sonraya bırakılması gerekir. Faktör temini, tipi ve dozu hakkında genellikle bu konularda tecrübeli ve donanımlı olan olan hasta ve hasta yakınlarından yardım almaktan çekinilmemelidir (Singleton et al, 2008). Faktör VIII'in bulunmadığı ya da temin edilene kadar çok zaman geçeceği düşünülen durumlarda taze donmuş plazma ve kriyopresipitat kullanılabilir (Pelligra SJ., 1987;Singleton et al, 2008).…”

Section: Discussionunclassified

Inguinal hematom nedeniyle acil serviste takip edilen hemofili olgusu

Erenler¹,

Yardan²,

Baydın³

et al. 2011

jecm

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Acil servise kasıkta şişlik ve ağrı yakınması ile başvuran 38 yaşında erkek hemofili A hastasını sunduk. Uzun yıllardır faktör VIII eksikliği nedeniyle tedavi alan ve pek çok defa acil servise başvuran hasta, ilk defa böylesi bir yakınma nedeni ile acil servise baş-vurmuştu. Durumun erken tanınmasının ve tedavi edilmesinin hastaların komplikasyonlardan korunmasında etkili olduğunu saptadık.J. Exp. Clin. Med., 2011; 28:189-191 ABSTRACTWe described a case report of a 38-year-old male hemophilia A patient who presented to our emergency department with swelling and pain on groin. Although he was medicated for factor VIII deficiency for many years and visited our department for many other reasons, this was the first time he presented with such a complaint. We pointed out that early diagnosis and treatment of this condition is cruical for preventing patients from complications.

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“…Krvavitev v to področje lahko ogroža bolnika, ker lahko povzroči zaporo dihalnih poti (109,110). Zato je potrebno takojšnje nadomestno zdravljenje še pred kakršnimi koli preiskavami.…”

Section: Krvavitev V žRelo In Vratunclassified

“…Nadomestno zdravljenje je potrebno, kadar je krvavitev obsežna ali če se ponavlja. Tedaj jo uvrščamo med hude krvavitve (109,110). Če kljub temu krvavitev vztraja oz.…”

Section: Nosunclassified

Nacionalna priporočila za obravnavo bolnikov s hemofilijo

et al. 2017

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The document presents recommendations for the comprehensive treatment of patients with haemophilia in Slovenia. It enables health workers at all three levels of health care to become well-acquainted with all the possible aspects of treatment based on the best practices of major centres worldwide, and on the studies and experience of health professionals at the National Haemophilia Centre, University Medical Center Ljubljana. The document contains definitions, treatment algorithms and lists of medications with their characteristics and appropriate dosages. It specifically defines indications for the exclusive competence of the tertiary level in Ljubljana due to the actual availability of teams and laboratory options. It also contains an extensive list of the literature on haemophilia.

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Emergency Department Care for Patients with Hemophilia and Von Willebrand Disease

Cited by 40 publications

References 11 publications

Management of bleeding and coagulopathy following major trauma: an updated European guideline

Management of bleeding and coagulopathy following major trauma: an updated European guideline

Inguinal hematom nedeniyle acil serviste takip edilen hemofili olgusu

Nacionalna priporočila za obravnavo bolnikov s hemofilijo

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