2022
DOI: 10.1016/j.ajem.2022.07.056
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Emergency department care of patients with Duchenne muscular dystrophy

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“…As age progresses, patients with DMD start to manifest altered cardiac parameters and respiratory weakness (1,2). While progressive respiratory failure remains the most common cause of death, increased life expectancy has revealed the importance of cardiomyopathy, which accounts for approximately 40% of deaths in the DMD population (3). In this context, it is important to understand the underlying molecular mechanisms causing dystrophic cardiomyopathy and heart failure to identify novel therapeutic targets.…”
Section: Introductionmentioning
confidence: 99%
“…As age progresses, patients with DMD start to manifest altered cardiac parameters and respiratory weakness (1,2). While progressive respiratory failure remains the most common cause of death, increased life expectancy has revealed the importance of cardiomyopathy, which accounts for approximately 40% of deaths in the DMD population (3). In this context, it is important to understand the underlying molecular mechanisms causing dystrophic cardiomyopathy and heart failure to identify novel therapeutic targets.…”
Section: Introductionmentioning
confidence: 99%