Emergency department visits and hospital admissions in kidney transplant recipients during the COVID-19 pandemic: A hospital-based study

Wongtanasarasin, Wachira; Phinyo, Phichayut

doi:10.5500/wjt.v12.i8.250

Cited by 3 publications

(1 citation statement)

References 18 publications

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“…Risk factors specific to the SOT population include age> 55 years, the use of anti-thymocyte globulin, retransplantation and the type of organ transplanted. The highest CDI rate is found in liver transplant recipients [22]. In our study, three patients had gastroenteritis.…”

Section: Discussionmentioning

confidence: 44%

Evaluation of infections in patients with kidney and liver transplantation

DOĞAN KAYA,

EVİK,

DENİZ

et al. 2023

The European Research Journal

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Objectives: Infection is a frequent complication of organ transplantation and is associated with significant morbidity and mortality. Methods: Patients who had liver and kidney transplants between 2011 and 2022, who were hospitalized in our hospital, and who were consulted for infectious diseases were retrospectively analyzed from hospital records. Results: Of the patients included in the study, 9 (28%) were female, 23 (72%) were male, and the mean age was 33.7 ± 11.3 years. Patients had congestive heart failure (87.2%, n = 28, hypertension (43.7%, n = 14), and chronic obstructive pulmonary disease (21.8%, n = 7). Twenty (62.5%) kidney transplant recipients and 12 (37.5%) liver transplant recipients were seen within ten years. The most common infections were urinary tract infection in 8 ( 25%) patients and pneumonia in 11 (34.3%). The other infections were gastrointestinal infections such as diarrhoea, bloodstream infections and COVID-19 and Cytomegalovirus. Culture-isolated organisms in 20 (62.5%) of the 32 patients admitted with infections. The microbiological data were notable for some unusual and opportunistic pathogens, including one case of acute cytomegalovirus viremia. Severe sepsis had been seen in six (18.75%) out of 32 patients with documented infections. Conclusions: Infection prevention has become a cornerstone of modern transplantation medicine due to the significant incidence of post-transplant infectious complications resulting from improved immunosuppressive therapies and surgical procedures.

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Section: Discussionmentioning

confidence: 44%

Evaluation of infections in patients with kidney and liver transplantation

DOĞAN KAYA,

EVİK,

DENİZ

et al. 2023

The European Research Journal

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Admissions Within the First Year After Kidney Transplantation: Evaluation of Risk Factors, Causes, and Outcomes

Ferreira,

Sarcinelli,

Alvarenga

2024

BJT

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Objectives: The aim of this study was to evaluate causes of hospital admission within the 1st year after kidney transplantation in a public hospital. Methods: This is a retrospective cohort. Data were collected by medical record review. Inclusion criteria were age older than 18 years and kidney transplant. Exclusion criteria were double transplant, primary graft failure, and in-hospital death after transplant procedure. Outcomes included 4-year patient survival (primary outcome), 1-year graft failure, and graft function in 1 year. Results: A total of 130 patients were evaluated. There was a predominance of male sex, glomerulonephritis, history of hemodialysis, first kidney transplant, and deceased donor kidneys. Hospital admission in the 1st year occurred in 71.5%. There were three deaths at the first admission (two had cardiovascular causes). The most frequent causes of admission were infections, rejection, and surgical complications. Less common causes included elective procedures such as peritoneal dialysis catheter removal. There was no statistically significant association between categorical and continuous variables studied and the occurrence of hospital admission. Also, hospital admission did not influence primary outcome or 1-year graft failure rate. However, it was associated with lower graft function at 1 year (both by serum creatinine and by estimated glomerular filtration rate – p < 0.05). Conclusion: There was a high incidence of hospital admission, and first admissions resulted in death in three patients (noninfectious causes). Considering the contribution of elective procedures to the high incidence of admission, we propose that hospital managers focus on improving the ability to solve such problems in the outpatient setting.

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Internações no Primeiro Ano Após o Transplante Renal: Avaliação de Fatores de Risco, Causas e Desfechos

Ferreira,

Sarcinelli,

Alvarenga

2024

BJT

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Objetivos: Este estudo objetivou avaliar as causas de internação no 1o ano após o transplante renal em um hospital público. Métodos: Trata-se de coorte retrospectiva feita por meio da revisão de prontuários médicos. Os critérios de inclusão foram 18 anos de idade ou mais e transplante renal. Os critérios de exclusão foram transplante duplo, falência primária do enxerto e óbito durante a internação para transplante. Os desfechos avaliados incluíram sobrevida global em 4 anos (desfecho primário), falência do enxerto em 1 ano e função do enxerto em 1 ano. Resultados: Dentre os 130 pacientes, predominavam osexo masculino, glomerulonefrite como etiologia, histórico de hemodiálise, primeiro transplante renal e rim de doador falecido. A taxa de internação no 1o ano após o transplante foi de 71,5%. Houve três óbitos na primeira internação (dois por eventos cardiovasculares). As principais causas de internação foram infecções, rejeição e complicações cirúrgicas. Causas menos comuns incluíam procedimentos eletivos, como a retirada do cateter de diálise peritoneal. Nenhuma das variáveis avaliadas teve associação estatisticamente significativa com risco aumentado para internação. Além disso, a ocorrência de internação não teve impacto na sobrevida global em 4 anos após o transplante (desfecho primário) e tampouco no risco de falência do enxerto em 1 ano. Porém, houve impacto negativo na função do enxerto ao final do 1o ano (tanto com o valor de creatinina quanto pela taxa de filtração glomerular estimada, com p < 0,05). Conclusão: Houve elevada frequência de internações, tendo a primeira resultado em óbito em três casos, nenhum de causa infecciosa. Considerando a contribuição de procedimentos considerados eletivos para tal estatística, propõe-se o investimento em resolutividade no nível ambulatorial em situações como retirada de cateter de Tenckhoff, tratamento dos casos leves de infecção pelo citomegalovírus (CMV ) e biópsia do enxerto renal.

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Emergency department visits and hospital admissions in kidney transplant recipients during the COVID-19 pandemic: A hospital-based study

Cited by 3 publications

References 18 publications

Evaluation of infections in patients with kidney and liver transplantation

Evaluation of infections in patients with kidney and liver transplantation

Admissions Within the First Year After Kidney Transplantation: Evaluation of Risk Factors, Causes, and Outcomes

Internações no Primeiro Ano Após o Transplante Renal: Avaliação de Fatores de Risco, Causas e Desfechos

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