“…Dr. Tocantins, a professor of medicine who conducted a series of animal studies examining IO infusions, explored the concept of IO infusions further. After completing a number of rabbit studies examining various fluids, such as dextrose, blood, and saline, he went on to report the successful IO infusions in nine pediatric patients with "impossible" intravenous access (De Sá, Melo, Dantas, & Delfim, 2012;Drinker, Drinker, & Lund, 1922;Luck, Haines, & Mull, 2010;Tocantins, 1940;Tocantins, O'Neill, & Jones, 1941). With the development of intravenous catheters, the IO needle was replaced as the favored instrument for vascular access.…”